{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T05:46:11Z","timestamp":1791783971172,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We evaluated experience with probe\u2010based near\u2010infrared autofluorescence (NIRAF) system (PTeye) in parathyroid gland (PTG) identification during total thyroidectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this retrospective study, patients undergoing total thyroidectomy using PTeye (2020\u20132022;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200984) were compared with a historical visual\u2010identification cohort (2018\u20132019;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009103).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PTG identification rates were comparable, although 42% of PTGs detected with PTeye were initially visualized with low or moderate confidence. Significantly fewer patients in the PTeye cohort had PTGs incidentally identified on histology (4.8% vs. 16.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018), but there was no difference in the incidence of autotransplanted PTGs or total inadvertent parathyroidectomy. Postoperative calcium was higher with PTeye (median 9.2 vs. 9.0\u2009mg\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Postoperative PTH, transient, and permanent hypoparathyroidism did not differ. An autofluorescence ratio cutoff of 2.5 improved specificity compared with the manufacturer\u2010recommended cutoff of 1.2.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PTeye provides adjunctive confirmation of suspected parathyroid tissue, including glands initially identified with low or moderate visual confidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70503","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T05:25:26Z","timestamp":1791782726000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Probe\u2010Based Near\u2010Infrared Autofluorescence for Parathyroid Identification During Thyroid Surgery: Clinical Outcomes, Surgeon Confidence, and Autofluorescence Thresholds"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7329-8560","authenticated-orcid":false,"given":"Anthony Y.","family":"Cheung","sequence":"first","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery, Massachusetts Eye and Ear Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Anesthesia &amp; Critical Care University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1029-3954","authenticated-orcid":false,"given":"Bo","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery, Massachusetts Eye and Ear Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Thyroid Surgery Fujian Medical University Union Hospital  Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-6775","authenticated-orcid":false,"given":"Yoshiyuki","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery, Massachusetts Eye and Ear Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5436-3649","authenticated-orcid":false,"given":"Marika D.","family":"Russell","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery, Massachusetts Eye and Ear Harvard Medical School  Boston Massachusetts 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