{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:35:36Z","timestamp":1791498936792,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HemaSphere"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1002\/hem3.70254","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T10:10:02Z","timestamp":1765188602000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of time to first progression and fitness status in elderly patients with mantle cell lymphoma: Results from the ELDERLY MANTLE\u2010FIRST study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4347-3775","authenticated-orcid":false,"given":"Francesca Maria","family":"Quaglia","sequence":"first","affiliation":[{"name":"UOC di Ematologia, DAI Medico Generale AOUI Verona  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Arcari","sequence":"additional","affiliation":[{"name":"Hematology Unit Ospedale Guglielmo da Saliceto Piacenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Morello","sequence":"additional","affiliation":[{"name":"Hematology Unit Ospedale Guglielmo da Saliceto Piacenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Marcheselli","sequence":"additional","affiliation":[{"name":"Fondazione Italiana Linfomi Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Tucci","sequence":"additional","affiliation":[{"name":"Hematology Division ASST Spedali Civili Brescia Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Pagani","sequence":"additional","affiliation":[{"name":"Hematology Division ASST Spedali Civili Brescia Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Bozzoli","sequence":"additional","affiliation":[{"name":"Hematology, P.O.V. Fazzi Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Scapinello","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Hematology University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2831-623X","authenticated-orcid":false,"given":"Francesco","family":"Piazza","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Hematology University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6915-2246","authenticated-orcid":false,"given":"Vittorio Ruggero","family":"Zilioli","sequence":"additional","affiliation":[{"name":"Division of Hematology ASST Grande Ospedale Metropolitano Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Muzi","sequence":"additional","affiliation":[{"name":"Division of Hematology ASST Grande Ospedale Metropolitano Niguarda Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Puccini","sequence":"additional","affiliation":[{"name":"Haematology Unit Careggi University Hospital Firenze Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Sordi","sequence":"additional","affiliation":[{"name":"Haematology Unit Careggi University Hospital Firenze Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Chiara","family":"Tisi","sequence":"additional","affiliation":[{"name":"Cell Therapy and Hematology San Bortolo Hospital Vicenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"Rampi","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hemato\u2010Oncology University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Castellino","sequence":"additional","affiliation":[{"name":"Department of Hematology Santa Croce e Carle Hospital Cuneo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Veronica","family":"Usai","sequence":"additional","affiliation":[{"name":"AO Brotzu\u2010Ospedale Oncologico Businco Unit of Hematology and Bone Marrow Transplant Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jari","family":"Paternoster","sequence":"additional","affiliation":[{"name":"Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Cencini","sequence":"additional","affiliation":[{"name":"Unit of Hematology Azienda Ospedaliera Universitaria Senese and University of Siena Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Ferrero","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Molecular Biotechnologies and Health Sciences University of Torino Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Consoli","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Molecular Biotechnologies and Health Sciences University of Torino Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Basso","sequence":"additional","affiliation":[{"name":"Oncohematology Unit Veneto Institute of Oncology IOV\u2010IRCCS Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Lucchini","sequence":"additional","affiliation":[{"name":"UCO Ematologia Azienda Sanitaria Universitaria Giuliano\u2010Isontina Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Pennese","sequence":"additional","affiliation":[{"name":"Hematology Unit, Department of Oncology and Hematology Spirito Santo Hospital Pescara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elena","family":"Nizzoli","sequence":"additional","affiliation":[{"name":"Division of Hematology Azienda Unit\u00e0 Sanitaria Locale\u2010IRCCS  Reggio Emilia Italy"},{"name":"Clinical and Experimental Medicine Doctorate School Universit\u00e0 degli Studi di Modena e Reggio Emilia  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Spina","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Immune\u2010Related Tumors Centro di Riferimento Oncologico di Aviano IRCCS Aviano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Pezzullo","sequence":"additional","affiliation":[{"name":"Hematology and Transplant Center University Hospital \u201cSan Giovanni di Dio e Ruggi d'Aragona\u201d Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Stella De","family":"Candia","sequence":"additional","affiliation":[{"name":"Hematology Unit IRCCS Istituto Tumori \u201cGiovanni Paolo II\u201d Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-7806","authenticated-orcid":false,"given":"Rita","family":"Tavarozzi","sequence":"additional","affiliation":[{"name":"SC Ematologia Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo Alessandria Italy"},{"name":"Department of Translational Medicine University of Eastern Piedmont Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Krampera","sequence":"additional","affiliation":[{"name":"UOC di Ematologia, DAI Medico Generale AOUI Verona  Italy"},{"name":"Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Visco","sequence":"additional","affiliation":[{"name":"UOC di Ematologia, DAI Medico Generale AOUI Verona  Italy"},{"name":"Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01620-2"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022015851"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx223"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15643"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-020-01013-3"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.27980"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-025-01241-9"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2023009804"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2021004765"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.02465"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.02370"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.00562"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000712"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18519"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17363"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bneo.2025.100128"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2201817"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO-25-00690"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2024-199710"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023022352"}],"container-title":["HemaSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hem3.70254","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hem3.70254","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hem3.70254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T08:00:15Z","timestamp":1777795215000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hem3.70254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/hem3.70254"],"URL":"https:\/\/doi.org\/10.1002\/hem3.70254","archive":["Portico"],"relation":{},"ISSN":["2572-9241","2572-9241"],"issn-type":[{"value":"2572-9241","type":"print"},{"value":"2572-9241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70254"}}