{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T11:40:12Z","timestamp":1733053212739,"version":"3.30.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":12480,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1981,7]]},"abstract":"\n \n The kinetics of plasma clearance of indocyanine green and bromosulfophthalein were studied in 49 consecutive patients with chronic unconjugated hyperbilirubinemia. Forty-four patients had Gilbert\u2019s syndrome whereas five patients had impaired hepatic uptake of indocyanine green and virtually normal hepatic bromosulfophthalein uptake. There was no difference in bilirubin metabolism between the two groups. A family study of the patients with impaired indocyanine green uptake revealed that the defect appears to be transmitted as an autosomal dominant trait associated with inheritance of impaired bilirubin metabolism. These patients manifest a novel disorder of organic anion transport which, like Gilbert\u2019s syndrome, is also characterized by chronic mild unconjugated hyperbilirubinemia.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/hep.1840010407","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T17:42:00Z","timestamp":1172943720000},"page":"319-324","update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["A constitutional unconjugated hyperbilirubinemia combined with indocyanine green intolerance: A new functional disorder?"],"prefix":"10.1097","volume":"1","author":[{"given":"Hideki","family":"Ohkubo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunio","family":"Okuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Iida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840010407-BIB1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0016-5085(19)33296-2","volume":"63","author":"Berk","year":"1972","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840010407-BIB2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0016-5085(76)80151-5","volume":"70","author":"Martin","year":"1976","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840010407-BIB3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00005792-195902000-00002","volume":"38","author":"Foulk","year":"1959","journal-title":"Medicine"},{"key":"10.1002\/hep.1840010407-BIB4","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1056\/NEJM195406172502402","volume":"250","author":"Read","year":"1954","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840010407-BIB5","first-page":"56","volume":"13","author":"Mich\u00e4elsson","year":"1961","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1002\/hep.1840010407-BIB6","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1093\/ajcp\/15.10.452","volume":"15","author":"Gaebler","year":"1945","journal-title":"Am J Clin Pathol"},{"key":"10.1002\/hep.1840010407-BIB7","first-page":"499","volume":"18","author":"Richards","year":"1959","journal-title":"Clin Sci"},{"key":"10.1002\/hep.1840010407-BIB8","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1749-6632.1970.tb37009.x","volume":"170","author":"Paumgartner","year":"1970","journal-title":"Ann NY Acad Sci"},{"key":"10.1002\/hep.1840010407-BIB9","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1007\/BF01314468","volume":"24","author":"Ohkubo","year":"1979","journal-title":"Digest Dis Sci"},{"key":"10.1002\/hep.1840010407-BIB10","first-page":"245","volume":"27","author":"Billing","year":"1964","journal-title":"Clin Sci"},{"key":"10.1002\/hep.1840010407-BIB11","first-page":"966","volume":"70","author":"Namihisa","year":"1973","journal-title":"Jpn J Gastroenterol"},{"key":"10.1002\/hep.1840010407-BIB12","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2957\/kanzo.15.223","volume":"15","author":"Kuchiba","year":"1974","journal-title":"Acta Hepatol Jpn"},{"key":"10.1002\/hep.1840010407-BIB13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2957\/kanzo.16.25","volume":"16","author":"Namihisa","year":"1975","journal-title":"Acta Hepatol Jpn"},{"key":"10.1002\/hep.1840010407-BIB14","first-page":"992","volume":"72","author":"Ohkubo","year":"1975","journal-title":"Jpn J Gastroenterol"},{"key":"10.1002\/hep.1840010407-BIB15","first-page":"1002","volume":"72","author":"Nambu","year":"1975","journal-title":"Jpn J Gastroenterol"},{"key":"10.1002\/hep.1840010407-BIB16","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1136\/gut.17.8.588","volume":"17","author":"Okuda","year":"1976","journal-title":"Gut"},{"key":"10.1002\/hep.1840010407-BIB17","first-page":"356","volume-title":"The liver. Quantitative aspects of structure and function","author":"Okuda","year":"1979","unstructured":"Constitutional selective defect in the hepatic transport of indocyanine green. In: , eds. The liver. Quantitative aspects of structure and function. 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