{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:51:54Z","timestamp":1762113114391,"version":"3.30.0"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":11322,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1984,9]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>This is the first report to document pit cells in the human liver. These cells were identified by characteristic electron-dense granules and rod-cored vesicles. The granules of human pit cells were smaller in number and size than those of the rat. In the present case of autoimmune hepatitis, pit cells and conventional agranular lymphocytes migrated into hepatic parenchyma and contacted degenerating and immature hepatocytes. Pit cells show natural killer activity (Kaneda et al., 1983), and may participate in development of lesions and cellular damage.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840040529","type":"journal-article","created":{"date-parts":[[2008,8,22]],"date-time":"2008-08-22T13:06:35Z","timestamp":1219410395000},"page":"955-958","update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":29,"title":["Pit Cell-Hepatocyte Contact in Autoimmune Hepatitis"],"prefix":"10.1097","volume":"4","author":[{"given":"Kenji","family":"Kaneda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narito","family":"Kurioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Seki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenjiro","family":"Wake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukeo","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840040529-BIB1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/BF00224305","article-title":"The pit cell: description of a new type of cell occuring in rat liver sinusoids and peripheral blood","volume":"173","author":"Wisse","year":"1976","journal-title":"Cell Tissue Res"},{"key":"10.1002\/hep.1840040529-BIB2","first-page":"153","volume-title":"Progress in liver diseases, Vol. VI","author":"Wisse","year":"1979"},{"key":"10.1002\/hep.1840040529-BIB3","first-page":"77","volume-title":"Sinusoidal liver cells","author":"Kaneda","year":"1982"},{"key":"10.1002\/hep.1840040529-BIB4","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/BF00212219","article-title":"Distribution and morphological characteristics of the pit cells in the liver of the rat","volume":"233","author":"Kaneda","year":"1983","journal-title":"Cell Tissue Res"},{"key":"10.1002\/hep.1840040529-BIB5","doi-asserted-by":"crossref","first-page":"567","DOI":"10.2220\/biomedres.4.567","article-title":"Pit cells as natural killer cells","volume":"4","author":"Kaneda","year":"1983","journal-title":"Biomed Res"},{"key":"10.1002\/hep.1840040529-BIB6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1600-065X.1979.tb00268.x","article-title":"Morphological and functional characterization of isolated effector cells responsible for human natural killer activity to fetal fibroblasts and to cultured cell line targets","volume":"44","author":"Saksela","year":"1979","journal-title":"Immunol Rev"},{"key":"10.1002\/hep.1840040529-BIB7","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1749-6632.1965.tb19000.x","article-title":"Autoimmune hepatitis","volume":"124","author":"Mackay","year":"1965","journal-title":"Ann NY Acad Sci"},{"key":"10.1002\/hep.1840040529-BIB8","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1679\/aohc1950.39.99","article-title":"Puncture perfusion of small tissue pieces for scanning electron microscopy","volume":"39","author":"Murakami","year":"1976","journal-title":"Arch Histol Jap"},{"key":"10.1002\/hep.1840040529-BIB9","first-page":"85","volume-title":"Sinusoidal liver cells","author":"Wilde","year":"1982"},{"key":"10.1002\/hep.1840040529-BIB10","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.2957\/kanzo.22.1099","article-title":"A histopathological study on the lesions observed in the periphery of the hepatic lobule and thought in the correlation of the progress to cirrhosis in chronic hepatitis (in Japanese with English abstract)","volume":"17","author":"Seki","year":"1981","journal-title":"Acta Hepatol Jap"},{"key":"10.1002\/hep.1840040529-BIB11","first-page":"102","volume-title":"Atlas of ultrastructure. Ultrastructural features in pathology","year":"1980","unstructured":"TsengCH (Editor). Atlas of ultrastructure. Ultrastructural features in pathology. New York: Appleton-Century-Crofts, 1980: 102-103."},{"key":"10.1002\/hep.1840040529-BIB12","first-page":"51","volume-title":"Progress in liver diseases","author":"Trump","year":"1976"},{"key":"10.1002\/hep.1840040529-BIB13","first-page":"393","article-title":"Electron microscopic studies of normal and proliferated bile ductules","volume":"38","author":"Schaffner","year":"1961","journal-title":"Am J Pathol"},{"key":"10.1002\/hep.1840040529-BIB14","first-page":"268","volume-title":"Gastroenterology","author":"Sherlock","year":"1976"},{"key":"10.1002\/hep.1840040529-BIB15","first-page":"310","article-title":"A quantitative ultrastructural analysis of the leukocytes in contact with hepatocytes in chronic active hepatitis, with a cytochemical detection of mononuclear phagocytes","volume":"109","author":"Bernuau","year":"1982","journal-title":"Am J Pathol"},{"key":"10.1002\/hep.1840040529-BIB16","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.4049\/jimmunol.130.5.2149","article-title":"Tissue distribution of human NK cells studied with anti-Leu-7 monoclonal antibody","volume":"130","author":"Si","year":"1983","journal-title":"J Immunol"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840040529","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-198409000-00029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T11:04:50Z","timestamp":1733051090000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-198409000-00029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,9]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1984]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840040529","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1984,9]]}}}