{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:19:02Z","timestamp":1763036342916,"version":"3.30.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Supplement 1","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":11566,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>The postoperative course of 138 transplants performed in 137 patients in the Cambridge and King\u2019s College Hospital series between May 2, 1968 and April 1, 1983 is presented. During the last 15 years, criteria for selection of transplant candidates has been improved and types of disease categories, both suitable and unsuitable for liver transplantation, have been defined. The acceptance of the concept of brain death and the use of heart-beating donors in the United Kingdom since 1976 has greatly improved the quality of donor organs. Changes in surgical technique, particularly with regard to biliary tract drainage, have reduced morbidity and mortality from biliary tract complications since 1975. The use of partial cardiopulmonary bypass in selected cases and changes in immunosuppressive drug regimens have not significantly improved our overall results. Despite these changes based on our experience, the perioperative mortality in the Cambridge and King\u2019s College Hospital series remains disturbingly high.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840040715","type":"journal-article","created":{"date-parts":[[2008,9,12]],"date-time":"2008-09-12T09:46:20Z","timestamp":1221212780000},"page":"50S-55S","update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":45,"title":["The Cambridge and King\u2019s College Hospital Experience of Liver Transplantation, 1968-1983"],"prefix":"10.1097","volume":"4","author":[{"given":"Keith","family":"Rolles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Neuberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy","family":"Calne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840040715-BIB1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0016-5085(79)90294-4","article-title":"Fifteen years of clinical liver transplantation","volume":"77","author":"Starzl","year":"1979","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840040715-BIB2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0002-9343(65)90178-6","article-title":"Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis. An unusual tumour with distinctive clinical and pathological features","volume":"38","author":"Klatskin","year":"1965","journal-title":"Am J Med"},{"key":"10.1002\/hep.1840040715-BIB3","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0140-6736(79)91668-4","article-title":"Use of partial cardiopulmonary bypass during the anhepatic phase of orthotopic liver grafting","volume":"2","author":"Calne","year":"1979","journal-title":"Lancet"},{"key":"10.1002\/hep.1840040715-BIB4","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/00000658-197611000-00012","article-title":"A new technique for biliary drainage in orthotopic liver transplantation utilizing the gall-bladder as a pedicle graft conduit between the donor and recipient common ducts","volume":"184","author":"Calne","year":"1976","journal-title":"Ann Surg"},{"key":"10.1002\/hep.1840040715-BIB5","first-page":"612","article-title":"Mismatched family donors for bone marrow transplantation for acute leukaemia","volume":"1","author":"Powles","year":"1983","journal-title":"Cancer"},{"key":"10.1002\/hep.1840040715-BIB6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM198201073060101","article-title":"Recurrence of primary biliary cirrhosis after liver grafting","volume":"306","author":"Neuberger","year":"1982","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840040715-BIB7","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(80)92481-2","article-title":"Effects of cyclosporin A on suppressor and inducer T lymphocytes in primary biliary cirrhosis","volume":"2","author":"Routhier","year":"1980","journal-title":"Lancet"},{"key":"10.1002\/hep.1840040715-BIB8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/hep.1840030114","article-title":"Relationship of pretransplant hepatobiliary disease to bile duct damage occurring in the liver allograft","volume":"3","author":"Fennell","year":"1983","journal-title":"Hepatology"},{"key":"10.1002\/hep.1840040715-BIB9","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1136\/bmj.1.6107.216","article-title":"Familial HBsAg hepatoma: treatment with orthotopic liver transplantation and specific immunoglobulin","volume":"1","author":"Johnson","year":"1978","journal-title":"Br Med J"},{"volume-title":"Liver transplantation","year":"1983","key":"10.1002\/hep.1840040715-BIB10","unstructured":"CalneRY, ed. Liver transplantation. London: Grune and Stratton, 1983."},{"key":"10.1002\/hep.1840040715-BIB11","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/S0140-6736(80)91785-7","article-title":"Survival and rehabilitation after orthotopic liver transplantation","volume":"1","author":"Macdougall","year":"1980","journal-title":"Lancet"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840040715","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-198401001-00014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T11:11:41Z","timestamp":1733051501000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-198401001-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":11,"journal-issue":{"issue":"Supplement 1","published-print":{"date-parts":[[1984]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840040715","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}