{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:37:02Z","timestamp":1770831422249,"version":"3.50.1"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":10045,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1988,3]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>In patients with portal hypertension and tense ascites, large-volume paracentesis improves patient comfort and may improve systemic hemodynamics. However, it has been avoided in nonedematous patients because of concern for complications, including intravascular volume depletion. In this study, 12 nonedematous patients with chronic liver disease, portal hypertension and tense ascites underwent 14 large-volume (5-liter) paracenteses for the relief of discomfort and\/or respiratory distress. Plasma volume was measured directly by a dilution method with <jats:sup>125<\/jats:sup>I-labeled human serum albumin prior to and at 24 or 48 hr after 13 of the paracenteses. All patients felt better postparacentesis. No dizziness, hypotension, tachycardia, encephalopathy or change in mean serum sodium, creatinine or blood urea nitrogen occurred. Two patients experienced a decrease in hematocrit, which was not explained by blood loss or increase in plasma volume. Mean plasma volume was 3,713 \u00b1 129 ml (55.1 \u00b1 1.5 ml per kg ideal body weight) preparacentesis and 3,684 \u00b1 136 ml postparacentesis, the difference being \u22120.78% (p = 0.48, NS). Our results suggest that 5-liter paracentesis in nonedematous patients with tense portal hypertension-related ascites improves patient comfort and is not associated with a decrease in measured plasma volume.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840080202","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T21:33:00Z","timestamp":1172957580000},"page":"207-210","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":65,"title":["Large-volume paracentesis in nonedematous patients with tense ascites: Its effect on intravascular volume"],"prefix":"10.1097","volume":"8","author":[{"given":"Paul C.","family":"Pinto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Amerian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Telfer B.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840080202-BIB1","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1056\/NEJM196703022760903","volume":"276","author":"Knauer","year":"1967","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840080202-BIB2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0002-9343(75)90350-2","volume":"59","author":"Guazzi","year":"1975","journal-title":"Am J Med"},{"key":"10.1002\/hep.1840080202-BIB3","first-page":"2223","volume":"62","author":"Liebowitz","year":"1962","journal-title":"NY St J Med"},{"key":"10.1002\/hep.1840080202-BIB4","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1056\/NEJM196101122640204","volume":"264","author":"Flood","year":"1961","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840080202-BIB5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/00325481.1967.11696108","volume":"41","author":"Baldus","year":"1967","journal-title":"Postgrad Med"},{"key":"10.1002\/hep.1840080202-BIB6","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/00005792-195812000-00002","volume":"37","author":"Papper","year":"1958","journal-title":"Medicine"},{"key":"10.1002\/hep.1840080202-BIB7","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1172\/JCI102948","volume":"33","author":"Gabuzda","year":"1954","journal-title":"J Clin Invest"},{"key":"10.1002\/hep.1840080202-BIB8","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1001\/jama.1951.02920240028007","volume":"145","author":"Holley","year":"1951","journal-title":"JAMA"},{"key":"10.1002\/hep.1840080202-BIB9","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1172\/JCI102487","volume":"30","author":"Nelson","year":"1951","journal-title":"J Clin Invest"},{"key":"10.1002\/hep.1840080202-BIB10","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/hep.1840050310","volume":"5","author":"Kao","year":"1985","journal-title":"Hepatology"},{"key":"10.1002\/hep.1840080202-BIB11","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1172\/JCI105622","volume":"46","author":"Lieberman","year":"1967","journal-title":"J Clin Invest"},{"key":"10.1002\/hep.1840080202-BIB12","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1365-2141.1973.tb01792.x","volume":"25","author":"Glass","year":"1973","journal-title":"Br J Haematol"},{"key":"10.1002\/hep.1840080202-BIB13","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1056\/NEJM196104272641702","volume":"264","author":"Williams","year":"1961","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840080202-BIB14","first-page":"750","volume":"30","author":"Berson","year":"1954","journal-title":"Bull NY Acad Med"},{"key":"10.1002\/hep.1840080202-BIB15","first-page":"503","volume":"47","author":"Moir","year":"1956","journal-title":"J Lab Clin Med"},{"key":"10.1002\/hep.1840080202-BIB16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.7326\/0003-4819-66-2-307","volume":"66","author":"McCloy","year":"1967","journal-title":"Ann Intern Med"},{"key":"10.1002\/hep.1840080202-BIB17","first-page":"468","volume":"11","author":"Hine","year":"1970","journal-title":"J Nucl Med"},{"key":"10.1002\/hep.1840080202-BIB18","volume-title":"Clinical chemistry, principles and techniques","author":"Henry","year":"1965","unstructured":"Clinical chemistry, principles and techniques. New York: Harper and Row, 1965."},{"key":"10.1002\/hep.1840080202-BIB19","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/hep.1840070302","volume":"7","author":"Simon","year":"1987","journal-title":"Hepatology"},{"key":"10.1002\/hep.1840080202-BIB20","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/S0016-5085(19)33111-7","volume":"65","author":"Itwatsuki","year":"1973","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840080202-BIB21","first-page":"s23","volume":"3","author":"Gin\u00e9s","year":"1986","journal-title":"J Hepatol"},{"key":"10.1002\/hep.1840080202-BIB22","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0016-5085(87)91007-9","volume":"93","author":"Gin\u00e9s","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840080202-BIB23","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1749-6632.1970.tb37014.x","volume":"170","author":"Lieberman","year":"1970","journal-title":"Ann NY Acad Sci"},{"key":"10.1002\/hep.1840080202-BIB24","first-page":"203","volume":"38","author":"Le Bolloc'h-Combrisson","year":"1963","journal-title":"Rev Med-Chir Mal Foie"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840080202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-198803000-00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T15:05:24Z","timestamp":1738940724000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-198803000-00001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,3]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840080202","relation":{},"ISSN":["0270-9139"],"issn-type":[{"value":"0270-9139","type":"print"}],"subject":[],"published":{"date-parts":[[1988,3]]}}}