{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T05:23:57Z","timestamp":1738992237205,"version":"3.37.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":9435,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1989,11]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>Sphincter of Oddi (SO) dysfunction is a recognised cause of postcholecystectomy pain, but a difficult condition to diagnose, requiring endoscopic biliary manometry (EBM) to confirm sphincter motor abnormalities. We have assessed quantitative cholescintigraphy in 19 postcholecystectomy (PC) patients with clinical and manometric evidence of SO dysfunction, 10 PC patients with non\u2013biliary type abdominal pain and 10 asymptomatic PC volunteers acting as controls to determine its value as a non\u2013invasive screening test. Quantitative <jats:sup>99m<\/jats:sup>Tc\u2013DISIDA scans lasted 60 minutes, activity\/time curves being created by computer analysis using the entire hepatobiliary system as region\u2013of\u2013interest (ROI). Scintigraphic analysis demonstrated that the time in minutes to maximum counts (T<jats:sub>max<\/jats:sub>) was significantly increased in the SO dysfunction group compared with the non\u2013biliary pain group and the asymptomatic volunteers (p &lt; 0.001). The per cent of biliary tracer emptied was also significantly less in the SO dysfunction group than either of the other groups at both 45 minutes (p &lt; 0.01) and 60 minutes (p &lt; 0.02). We conclude that quantitative cholescintigraphy may be a valuable non\u2013invasive screening test in clinically suspected SO dysfunction.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840100526","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T22:43:45Z","timestamp":1172961825000},"page":"895-896","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["99MTc\u2013Disida Vs. Endoscopic Biliary Manometry in Assessing Sphincter of Oddi Function"],"prefix":"10.1097","volume":"10","author":[{"given":"Simon","family":"Bar-Meir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Chamovitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840100526-BIB1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF01308431","volume":"24","author":"Bar-Meir","year":"1979","journal-title":"Dig Dis Sci"},{"key":"10.1002\/hep.1840100526-BIB2","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/hep.1840040225","volume":"4","author":"Bar-Meir","year":"1984","journal-title":"Hepatology"},{"key":"10.1002\/hep.1840100526-BIB3","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1148\/radiology.156.3.4023245","volume":"156","author":"Lee","year":"1985","journal-title":"Radiology"},{"key":"10.1002\/hep.1840100526-BIB4","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/0016-5085(86)91130-3","volume":"90","author":"Shaffer","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840100526-BIB5","first-page":"191","volume":"26","author":"Pace","year":"1983","journal-title":"Can J Surg"},{"key":"10.1002\/hep.1840100526-BIB6","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S0016-5085(81)80010-8","volume":"81","author":"Joshi","year":"1981","journal-title":"Gastroenterology"},{"key":"10.1002\/hep.1840100526-BIB7","first-page":"94","volume":"78","author":"Bar-Meir","year":"1983","journal-title":"Am J Gastroenterol"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840100526","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-198911000-00025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T15:24:36Z","timestamp":1738941876000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-198911000-00025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,11]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1989]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840100526","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1989,11]]}}}