{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:32:32Z","timestamp":1759991552955,"version":"3.37.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":9343,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1990,2]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>A patient with acute myeloblastic leukaemia developed jaundice revealing peliosis hepatis after receiving 6\u2013thioguanine for two months. Peliosis hepatis was severe and was associated with mild lesions of centrilobular veins. Withdrawal of 6\u2013thioguanine was followed by a progressive improvement of liver dysfunction. This report shows that 6\u2013thioguanine, a thiopurine already reported to be responsible for veno\u2013occlusive disease of the liver, can induce peliosis hepatis. This suggests that some liver vascular disorders caused by thiopurines (6\u2013thioguanine, azathioprine and 6\u2013mercaptopurine), particularly peliosis hepatis, veno\u2013occlusive disease, sinusoidal dilatation and perisinusoidal fibrosis, might be related syndromes caused by similar lesions at different sites.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840110225","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:17:00Z","timestamp":1172963820000},"page":"322-323","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["An Additional Argument for A Toxic Mechanism of Peliosis Hepatis in Man"],"prefix":"10.1097","volume":"11","author":[{"given":"Elie Serge","family":"Zafrani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840110225-BIB1","first-page":"349","volume":"114","author":"Zafrani","year":"1984","journal-title":"Am J Pathol"},{"key":"10.1002\/hep.1840110225-BIB2","first-page":"207","volume-title":"Sinusoids in human liver: health and disease","author":"Zafrani","year":"1988","unstructured":". Primary lesions of the hepatic sinusoid. In: , eds. Sinusoids in human liver: health and disease. Rijswijk, The Netherlands: The Kupffer Cell Foundation, 1988: 207\u2013222."},{"key":"10.1002\/hep.1840110225-BIB3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1001\/archinte.1983.00350030109018","volume":"143","author":"Zafrani","year":"1983","journal-title":"Arch Intern Med"},{"key":"10.1002\/hep.1840110225-BIB4","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1136\/gut.19.8.748","volume":"19","author":"Degott","year":"1978","journal-title":"Gut"},{"key":"10.1002\/hep.1840110225-BIB5","first-page":"405","volume":"104","author":"Kosek","year":"1980","journal-title":"Arch Pathol Lab Med"},{"key":"10.1002\/hep.1840110225-BIB6","first-page":"38","volume":"131","author":"Scoazec","year":"1988","journal-title":"Am J Pathol"},{"key":"10.1002\/hep.1840110225-BIB7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0046-8177(87)80054-0","volume":"18","author":"Zafrani","year":"1987","journal-title":"Hum Pathol"},{"key":"10.1002\/hep.1840110225-BIB8","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1002\/hep.1840060510","volume":"6","author":"Gaulard","year":"1986","journal-title":"HEPATOLOGY"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840110225","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-199002000-00024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T15:29:11Z","timestamp":1738942151000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-199002000-00024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,2]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840110225","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1990,2]]}}}