{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T05:24:16Z","timestamp":1738992256679,"version":"3.37.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":9343,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1990,2]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>Genetic disorders were identified infrequently among children presenting with Reye's syndrome in the past. During a two\u2013year period, we evaluated four consecutive patients referred for intensive care of Reye's syndrome. A standard investigation for inborn errors of metabolism revealed that two patients had enzymatic defects of fatty acid oxidation, and the other two had partial deficiencies of ornithine transcarbamoylase. None had experienced a previous episode of Reye's syndrome, and three of the four had been entirely healthy in the past. Our experience suggests that as the incidence of Reye's syndrome has decreased, patients with its clinical features are now more likely to have manageable inborn errors of metabolism (e. g. disorders of ureagenesis, ketogenesis, and branched\u2013chain amino acids).<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840110228","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:17:00Z","timestamp":1172963820000},"page":"327-328","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Changing Trends of Inborn Errors in Reye's Syndrome: Rarity Is Relative"],"prefix":"10.1097","volume":"11","author":[{"given":"Edward Y.","family":"Hsia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1002\/hep.1840110228-BIB1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0140-6736(63)90554-3","volume":"2","author":"Reye","year":"1963","journal-title":"Lancet"},{"key":"10.1002\/hep.1840110228-BIB2","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1001\/jama.1987.03390140075030","volume":"257","author":"Hurwitz","year":"1987","journal-title":"JAMA"},{"key":"10.1002\/hep.1840110228-BIB3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archpedi.1976.02120040019004","volume":"130","author":"Thaler","year":"1976","journal-title":"Am J Dis Child"},{"key":"10.1002\/hep.1840110228-BIB4","first-page":"66","volume":"35","year":"1986","journal-title":"MMWR"},{"key":"10.1002\/hep.1840110228-BIB5","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1542\/peds.79.3.382","volume":"79","author":"Taubman","year":"1987","journal-title":"Pediatrics"},{"key":"10.1002\/hep.1840110228-BIB6","first-page":"250","volume":"1","year":"1989","journal-title":"Lancet"},{"key":"10.1002\/hep.1840110228-BIB7","volume-title":"Mendelian Inheritance in Man: catalogs of autosomal dominant, autosomal recessive, and X-linked phenotypes","author":"McKusick","year":"1988","unstructured":"Mendelian Inheritance in Man: catalogs of autosomal dominant, autosomal recessive, and X-linked phenotypes. 8th ed. Baltimore: Johns Hopkins University Press, 1988."},{"key":"10.1002\/hep.1840110228-BIB8","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1056\/NEJM198611063151903","volume":"315","author":"Yokosuka","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1002\/hep.1840110228-BIB9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1056\/NEJM198901193200305","volume":"320","author":"Antonarakis","year":"1989","journal-title":"N Engl J Med"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840110228","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-199002000-00027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T15:32:39Z","timestamp":1738942359000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-199002000-00027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,2]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840110228","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1990,2]]}}}