{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:44:44Z","timestamp":1786977884992,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3956,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Fondo de Investigaciones Sanitarias","award":["FIS 02\/0692"],"award-info":[{"award-number":["FIS 02\/0692"]}]},{"name":"Fondo de Investigaciones Sanitarias","award":["FIS 02\/0739"],"award-info":[{"award-number":["FIS 02\/0739"]}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"crossref","award":["C 03\/02"],"award-info":[{"award-number":["C 03\/02"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Fondo de Investigaci\u00f3n Sanitaria","award":["BEFI 538\/03"],"award-info":[{"award-number":["BEFI 538\/03"]}]},{"name":"Ministerio de Sanidad y Consumo","award":["CM 0300123"],"award-info":[{"award-number":["CM 0300123"]}]},{"name":"Fundaci\u00f3n Carolina, Ministerio de Educaci\u00f3n y Cultura"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Transjugular intrahepatic portosystemic shunt (TIPS) have been shown to be an efficient portal-systemic derivative treatment for Budd-Chiari syndrome (BCS) patients uncontrolled by medical therapy. However, the main drawback of TIPS for this condition is a very high rate of shunt dysfunction. Recently, polytetrafluoroethylene (PTFE)-covered stents have been shown to reduce the incidence of TIPS dysfunction in patients with cirrhosis. The aim of the study was to assess the incidence of TIPS dysfunction in 2 cohorts of BCS patients treated with bare or PTFE-covered stents. The study included 25 TIPS procedures (16 bare stents and 9 covered stents) with a median follow-up period of 20.4 months (range, 3.9-124.8). Fourteen of 16 patients (87%) receiving bare stents had TIPS dysfunction compared to 3 of the 9 patients (33%) receiving PTFE-covered stents (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .005). The actuarial rates of primary patency in the bare-stent group were 19% at 1 year compared with 67% in the PTFE-covered stent group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .02; log-rank test). The number of additional interventional procedures to maintain TIPS patency was significantly greater in the bare-stent than in the PTFE-covered stent group (1.9 \u00b1 1.2 vs. 0.6 \u00b1 0.9;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .007). The number of patients with clinical relapses was greater in the bare-stent group compared to the PTFE-covered stent group (13 vs. 5 episodes in 9 and 3 patients, respectively).\n                      <jats:underline>In conclusion<\/jats:underline>\n                      , PTFE-covered stents have a considerable advantage over bare stents for the TIPS treatment of BCS patients, with a lower dysfunction rate, a lower number of reinterventions, and fewer prosthesis requirements. PTFE-covered stents are preferable in patients with Budd-Chiari Syndrome. (Hepatology 2004;40:1197-1202.)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hep.20436","type":"journal-article","created":{"date-parts":[[2004,10,14]],"date-time":"2004-10-14T19:01:47Z","timestamp":1097780507000},"page":"1197-1202","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":138,"title":["PTFE-covered stents improve TIPS patency in Budd-Chiari syndrome"],"prefix":"10.1097","volume":"40","author":[{"given":"Manuel","family":"Hern\u00e1ndez-Guerra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Turnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Rubinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Olliff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elwyn","family":"Elias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Bosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Garc\u00eda-Pag\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-22-20241201","doi-asserted-by":"crossref","first-page":"364371","DOI":"10.1016\/S0168-8278(02)00434-8","article-title":"Budd-Chiari syndrome: a review by an expert panel.","volume":"38","author":"Janssen","year":"2003","journal-title":"J Hepatol"},{"key":"R2-22-20241201","doi-asserted-by":"crossref","first-page":"488496","DOI":"10.1002\/hep.510270224","article-title":"Pathology of the liver in Budd-Chiari syndrome: portal vein thrombosis and the histogenesis of veno-centric cirrhosis, veno-portal cirrhosis, and large regenerative nodules.","volume":"27","author":"Tanaka","year":"1998","journal-title":"HEPATOLOGY"},{"key":"R3-22-20241201","doi-asserted-by":"crossref","first-page":"522527","DOI":"10.1097\/00000658-200104000-00007","article-title":"Budd-Chiari syndrome: current management options.","volume":"233","author":"Slakey","year":"2001","journal-title":"Ann Surg"},{"key":"R4-22-20241201","first-page":"276281","article-title":"Portosystemic shunt in Budd-Chiari syndrome: long-term survival and factors affecting shunt patency in 25 patients in Western countries.","volume":"115","author":"Panis","year":"1994","journal-title":"Surgery"},{"key":"R5-22-20241201","doi-asserted-by":"crossref","first-page":"8489","DOI":"10.1002\/hep.510300125","article-title":"Outcome of Budd-Chiari syndrome: a multivariate analysis of factors related to survival including surgical portosystemic shunting.","volume":"30","author":"Zeitoun","year":"1999","journal-title":"HEPATOLOGY"},{"key":"R6-22-20241201","first-page":"793803","article-title":"The diagnosis and management of the Budd-Chiari syndrome: consensus and controversies.","volume":"38","author":"Valla","year":"2003","journal-title":"HEPATOLOGY"},{"key":"R7-22-20241201","doi-asserted-by":"crossref","first-page":"217225","DOI":"10.1016\/S0168-8278(05)80249-1","article-title":"Transjugular intrahepatic portosystemic stent-shunt (TIPS) in the treatment of Budd-Chiari syndrome.","volume":"18","author":"Ochs","year":"1993","journal-title":"J Hepatol"},{"key":"R8-22-20241201","doi-asserted-by":"crossref","first-page":"263267","DOI":"10.1016\/S1051-0443(93)71849-7","article-title":"Treatment of Budd-Chiari syndrome with a transjugular intrahepatic portosystemic shunt.","volume":"4","author":"Peltzer","year":"1993","journal-title":"J Vasc Interv Radiol"},{"key":"R9-22-20241201","doi-asserted-by":"crossref","first-page":"805811","DOI":"10.1148\/radiology.197.3.7480760","article-title":"Budd-Chiari syndrome: technical, hemodynamic, and clinical results of treatment with transjugular intrahepatic portosystemic shunt.","volume":"197","author":"Blum","year":"1995","journal-title":"Radiology"},{"key":"R10-22-20241201","first-page":"603608","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS) for Budd-Chiari syndrome or portal vein thrombosis: review of indications and problems.","volume":"94","author":"Ganger","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"R11-22-20241201","doi-asserted-by":"crossref","first-page":"131136","DOI":"10.1016\/S1051-0443(07)61817-X","article-title":"Quality improvement guidelines for transjugular intrahepatic portosystemic shunts. SCVIR Standards of Practice Committee.","volume":"12","author":"Haskal","year":"2001","journal-title":"J Vasc Interv Radiol"},{"key":"R12-22-20241201","doi-asserted-by":"crossref","first-page":"132139","DOI":"10.1053\/jhep.2002.30274","article-title":"TIPS is a useful long-term derivative therapy for patients with Budd-Chiari syndrome uncontrolled by medical therapy.","volume":"35","author":"Perello","year":"2002","journal-title":"HEPATOLOGY"},{"key":"R13-22-20241201","doi-asserted-by":"crossref","first-page":"12771283","DOI":"10.1016\/0016-5085(94)90020-5","article-title":"Incidence of shunt occlusion or stenosis following transjugular intrahepatic portosystemic shunt placement.","volume":"106","author":"Lind","year":"1994","journal-title":"Gastroenterology"},{"key":"R15-22-20241201","doi-asserted-by":"crossref","first-page":"130133","DOI":"10.1136\/gut.52.1.130","article-title":"Acute propranolol administration effectively decreases portal pressure in patients with TIPS dysfunction.","volume":"52","author":"Bellis","year":"2003","journal-title":"Gut"},{"key":"R16-22-20241201","doi-asserted-by":"crossref","first-page":"12961303","DOI":"10.1016\/S0016-5085(98)70436-6","article-title":"Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings.","volume":"114","author":"Casado","year":"1998","journal-title":"Gastroenterology"},{"issue":"Suppl 1","key":"R17-22-20241201","first-page":"416A","article-title":"Long-term survival after portosystemic shunting for Budd-Chiari syndrome. 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shunt.","volume":"25","author":"Cejna","year":"2002","journal-title":"Cardiovasc Intervent Radiol"},{"key":"R31-22-20241201","doi-asserted-by":"crossref","first-page":"337345","DOI":"10.1007\/s002680020380","article-title":"Transjugular intrahepatic portosystemic shunt: present status, comparison with endoscopic therapy and shunt surgery, and future prospectives.","volume":"25","author":"Rosch","year":"2001","journal-title":"World J Surg"},{"key":"R32-22-20241201","doi-asserted-by":"crossref","first-page":"682688","DOI":"10.1148\/radiology.205.3.9393521","article-title":"PTFE-encapsulated endovascular stent-graft for transjugular intrahepatic portosystemic shunts: experimental 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