{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:18:00Z","timestamp":1773220680101,"version":"3.50.1"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3440,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1002\/hep.21097","type":"journal-article","created":{"date-parts":[[2006,3,23]],"date-time":"2006-03-23T18:50:39Z","timestamp":1143139839000},"page":"837-846","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":38,"title":["Intestinal mucosal alterations in rats with carbon tetrachloride\u2010induced cirrhosis"],"prefix":"10.1097","volume":"43","author":[{"given":"Sathish Kumar","family":"Natarajan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhu","family":"Ramamoorthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simmy","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayasree","family":"Basivireddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gagandeep","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anup","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna B","family":"Pulimood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.A.","family":"Balasubramanian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-26-20241201","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/gut.28.5.623","article-title":"Problems of bacterial infection in patients with liver disease","volume":"28","author":"Wyke","year":"1987","journal-title":"Gut"},{"key":"R2-26-20241201","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1080\/00365520150218110","article-title":"Small intestinal bacterial overgrowth versus antimicrobial capacity in patients with spontaneous bacterial peritonitis","volume":"36","author":"Chang","year":"2001","journal-title":"Scand J Gastroenterol"},{"key":"R3-26-20241201","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0022-4804(03)00112-4","article-title":"Bacterial translocation after cirrhotic liver resection: a clinical investigation of 181 patients","volume":"111","author":"Yeh","year":"2003","journal-title":"J Surg Res"},{"key":"R4-26-20241201","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1136\/gut.35.11.1648","article-title":"Bacterial translocation in cirrhotic rats. Its role in the development of spontaneous bacterial peritonitis","volume":"35","author":"Llovet","year":"1994","journal-title":"Gut"},{"key":"R5-26-20241201","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1097\/00042737-200309000-00005","article-title":"Gastroduodenal and intestinal permeability in primary biliary cirrhosis","volume":"15","author":"Di Leo","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"R6-26-20241201","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/00004836-198208000-00011","article-title":"Activation of the alternative complement pathway in ascitic fluid during spontaneous bacterial peritonitis","volume":"4","author":"Fromkes","year":"1982","journal-title":"J Clin Gastroenterol"},{"key":"R7-26-20241201","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/S0168-8278(97)80474-6","article-title":"Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites","volume":"26","author":"Guarner","year":"1997","journal-title":"J Hepatol"},{"key":"R8-26-20241201","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.jss.2003.12.029","article-title":"Altered glycosylation of surfactant and brush border membrane of the small intestine in response to surgical manipulation","volume":"117","author":"Prabhu","year":"2004","journal-title":"J Surg Res"},{"key":"R9-26-20241201","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1074\/jbc.M109958200","article-title":"Tumor necrosis factor alpha increases the expression of glycosyltransferases and sulfotransferases responsible for the biosynthesis of sialylated and\/or sulfated Lewis x epitopes in the human bronchial mucosa","volume":"277","author":"Delmotte","year":"2002","journal-title":"J Biol Chem"},{"key":"R10-26-20241201","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0021-5198(19)39718-5","article-title":"Inhibition of gastric glucosamine synthetase activity by oxygen radicals: a possible cause of decreased mucosal protective capacity","volume":"58","author":"Tatsumi","year":"1992","journal-title":"Jpn J Pharmacol"},{"key":"R11-26-20241201","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/01.sla.0000133119.38175.97","article-title":"Surgical manipulation of the intestine results in quantitative and qualitative alterations in luminal Escherichia coli","volume":"240","author":"Thomas","year":"2004","journal-title":"Ann Surg"},{"key":"R12-26-20241201","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/jhep.2002.31656","article-title":"Intestinal mucosal alterations in experimental cirrhosis in the rat: role of oxygen free radicals","volume":"35","author":"Ramachandran","year":"2002","journal-title":"HEPATOLOGY"},{"key":"R13-26-20241201","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1046\/j.1365-2168.2000.01469.x","article-title":"Role of xanthine oxidase in small bowel mucosal dysfunction after surgical stress","volume":"87","author":"Anup","year":"2000","journal-title":"Br J Surg"},{"key":"R14-26-20241201","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1440-1746.2001.02444.x","article-title":"Intestinal dysfunction in liver cirrhosis: its role in spontaneous bacterial peritonitis","volume":"16","author":"Ramachandran","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"R15-26-20241201","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0016-5085(82)80126-1","article-title":"High yield micronodular cirrhosis in the rat","volume":"83","author":"Proctor","year":"1982","journal-title":"Gastroenterology"},{"key":"R16-26-20241201","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-2697(81)90261-X","article-title":"A simple method to determine nanogram levels of 4\u2010hydroxyproline in biological tissues","volume":"112","author":"Jamall","year":"1981","journal-title":"Anal Biochem"},{"key":"R17-26-20241201","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"Am J Clin Pathol"},{"key":"R18-26-20241201","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1471-4159.1977.tb10699.x","article-title":"Purification and properties of brain alkaline phosphatase","volume":"29","author":"Dorai","year":"1977","journal-title":"J Neurochem"},{"key":"R19-26-20241201","first-page":"1004","article-title":"A modified Malloy\u2010Evelyn procedure for total bilirubin in microsamples","volume":"43","author":"Shihabi","year":"1977","journal-title":"Am J Med Technol"},{"key":"R20-26-20241201","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"R21-26-20241201","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1042\/bj2180441","article-title":"Preparation of rat enterocyte mitochondria","volume":"218","author":"Masola","year":"1984","journal-title":"Biochem J"},{"key":"R22-26-20241201","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1006\/abbi.1999.1185","article-title":"Nitric oxide prevents anoxia\u2010induced apoptosis in colonic HT29 cells","volume":"366","author":"Madesh","year":"1999","journal-title":"Arch Biochem Biophys"},{"key":"R23-26-20241201","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1042\/bj2940719","article-title":"Oxidative damage to mitochondria is mediated by the Ca(2+)\u2010dependent inner\u2010membrane permeability transition","volume":"294","author":"Takeyama","year":"1993","journal-title":"Biochem J"},{"key":"R24-26-20241201","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1023\/A:1006871622049","article-title":"Enterocyte viability and mitochondrial function after graded intestinal ischemia and reperfusion in rats","volume":"167","author":"Madesh","year":"1997","journal-title":"Mol Cell Biochem"},{"key":"R25-26-20241201","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/abio.2000.4908","article-title":"A novel method of preparation of small intestinal brush border membrane vesicles by polyethylene glycol precipitation","volume":"289","author":"Prabhu","year":"2001","journal-title":"Anal Biochem"},{"key":"R26-26-20241201","doi-asserted-by":"crossref","first-page":"20614","DOI":"10.1016\/S0021-9258(19)47107-X","article-title":"Isolation and characterization of a small intestinal surfactant\u2010like particle containing alkaline phosphatase and other digestive enzymes","volume":"264","author":"Eliakim","year":"1989","journal-title":"J Biol Chem"},{"key":"R27-26-20241201","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/0006-2952(88)90800-3","article-title":"Fatty acid\u2010induced alterations in transport systems of the small intestinal brush\u2010border membrane","volume":"37","author":"Tiruppathi","year":"1988","journal-title":"Biochem Pharmacol"},{"key":"R28-26-20241201","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0003-2697(90)90556-O","article-title":"A spectrophotometric method for simultaneous determination of protein\u2010bound hexoses and fucose with a mixture of L\u2010cysteine and phenol","volume":"188","author":"Djurdjic","year":"1990","journal-title":"Anal Biochem"},{"key":"R29-26-20241201","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0009-8981(62)90086-4","article-title":"Photometric determination of sialic acids in serum and cerebrospinal fluid with the thiobarbituric acid method","volume":"7","author":"Saifer","year":"1962","journal-title":"Clin Chim Acta"},{"key":"R31-26-20241201","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"R32-26-20241201","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02532979","article-title":"Autoxidation of methyl linoleate. Separation and analysis of isomeric mixtures of methyl linoleate hydroperoxides and methyl hydroxylinoleates","volume":"12","author":"Chan","year":"1977","journal-title":"Lipids"},{"key":"R33-26-20241201","doi-asserted-by":"crossref","first-page":"7255","DOI":"10.1073\/pnas.90.15.7255","article-title":"Protein oxidative damage is associated with life expectancy of houseflies","volume":"90","author":"Sohal","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R34-26-20241201","first-page":"G768","article-title":"Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine: a reevaluation","volume":"254","author":"Parks","year":"1988","journal-title":"Am J Physiol"},{"key":"R35-26-20241201","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1128\/jcm.33.8.2204-2205.1995","article-title":"Evaluation of a simplified HEp\u20102 cell adherence assay for Escherichia coli isolated from south Indian children with acute diarrhea and controls","volume":"33","author":"Kang","year":"1995","journal-title":"J Clin Microbiol"},{"key":"R36-26-20241201","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1128\/IAI.70.1.412-415.2002","article-title":"Contribution of choline\u2010binding proteins to cell surface properties of Streptococcus pneumoniae","volume":"70","author":"Swiatlo","year":"2002","journal-title":"Infect Immun"},{"key":"R37-26-20241201","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1128\/iai.30.2.531-537.1980","article-title":"Effect of carbohydrates on adherence of Escherichia coli to human urinary tract epithelial cells","volume":"30","author":"Schaeffer","year":"1980","journal-title":"Infect Immun"},{"key":"R38-26-20241201","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1128\/iai.65.10.4135-4145.1997","article-title":"Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli","volume":"65","author":"Czeczulin","year":"1997","journal-title":"Infect Immun"},{"key":"R39-26-20241201","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1023\/A:1018899611006","article-title":"Altered small bowel motility in patients with liver cirrhosis depends on severity of liver disease","volume":"42","author":"Madrid","year":"1997","journal-title":"Dig Dis Sci"},{"key":"R40-26-20241201","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/hep.510310109","article-title":"Effect of propranolol on the factors promoting bacterial translocation in cirrhotic rats with ascites","volume":"31","author":"Perez\u2010Paramo","year":"2000","journal-title":"HEPATOLOGY"},{"key":"R41-26-20241201","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1111\/j.1572-0241.2003.07475.x","article-title":"Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension","volume":"98","author":"Gunnarsdottir","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"R42-26-20241201","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1111\/j.1572-0241.2001.03636.x","article-title":"Long\u2010term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function","volume":"96","author":"Madrid","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"R43-26-20241201","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1128\/iai.64.2.606-610.1996","article-title":"Transferrin associated with the porcine intestinal mucosa is a receptor specific for K88ab fimbriae of Escherichia coli","volume":"64","author":"Grange","year":"1996","journal-title":"Infect Immun"},{"key":"R44-26-20241201","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/978-1-4899-1828-4_40","article-title":"Binding of human enterotoxigenic Escherichia coli expressing coli surface antigen 6 to rabbit intestinal enterocytes and glycoproteins","volume":"412","author":"Helander","year":"1997","journal-title":"Adv Exp Med Biol"},{"key":"R45-26-20241201","doi-asserted-by":"crossref","first-page":"441","DOI":"10.33549\/physiolres.930000.49.441","article-title":"Role of mucus in ischemia\/reperfusion\u2010induced gastric mucosal injury in rats","volume":"49","author":"Mojzis","year":"2000","journal-title":"Physiol Res"},{"key":"R46-26-20241201","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/00000658-199010000-00012","article-title":"The process of microbial translocation","volume":"212","author":"Alexander","year":"1990","journal-title":"Ann Surg"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.21097","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-200604000-00026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T07:05:47Z","timestamp":1733036747000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-200604000-00026"}},"subtitle":["Changes in glycosylation and luminal bacteria\u2020"],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.21097","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.12495.469979","asserted-by":"object"}]},"ISSN":["0270-9139"],"issn-type":[{"value":"0270-9139","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}