{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T23:56:16Z","timestamp":1771545376837,"version":"3.50.1"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2892,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:sec>\n            <jats:title\/>\n          <\/jats:sec>","DOI":"10.1002\/hep.21871","type":"journal-article","created":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T19:53:43Z","timestamp":1190750023000},"page":"963-965","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":22,"title":["Geotherapeutics of primary biliary cirrhosis"],"prefix":"10.1097","volume":"46","author":[{"given":"Christophe","family":"Corpechot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoul","family":"Poupon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-4-20241201","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0140-6736(97)04248-7","article-title":"The UK general practice research database.","volume":"350","author":"Walley","year":"1997","journal-title":"Lancet"},{"key":"R3-4-20241201","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1053\/gast.2002.36027","article-title":"Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: followup for up to 28 years.","volume":"123","author":"Prince","year":"2002","journal-title":"Gastroenterology"},{"key":"R4-4-20241201","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1056\/NEJMra043898","article-title":"Primary biliary cirrhosis.","volume":"353","author":"Kaplan","year":"2005","journal-title":"N Engl J Med"},{"key":"R5-4-20241201","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/S0016-5085(97)70183-5","article-title":"Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis.","volume":"113","author":"Poupon","year":"1997","journal-title":"Gastroenterology"},{"key":"R6-4-20241201","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0140-6736(98)11293-X","article-title":"Randomised controlled trials of ursodeoxycholicacid therapy for primary biliary cirrhosis: a metaanalysis.","volume":"354","author":"Goulis","year":"1999","journal-title":"Lancet"},{"key":"R8-4-20241201","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(05)72401-6","article-title":"Ursodeoxycholic acid for primary biliary cirrhosis.","volume":"355","author":"Lindor","year":"2000","journal-title":"Lancet"},{"key":"R9-4-20241201","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1572-0241.2006.00634.x","article-title":"Longterm effects of middose ursodeoxycholic acid in primary biliary cirrhosis: a metaanalysis of randomized controlled trials.","volume":"101","author":"Shi","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"R10-4-20241201","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1572-0241.2007.01235.x","article-title":"Ursodeoxycholic acid for patients with primary biliary cirrhosis: an updated systematic review and metaanalysis of randomized clinical trials using Bayesian approach as sensitivity analyses.","volume":"102","author":"Gong","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"R11-4-20241201","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0168-8278(99)80136-6","article-title":"Comparison of three doses of ursodeoxycholic acid in the treatment of primary biliary cirrhosis: a randomized trial.","volume":"30","author":"Angulo","year":"1999","journal-title":"J Hepatol"},{"key":"R12-4-20241201","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0168-8278(03)00192-2","article-title":"Combined analysis of the effect of treatment with ursodeoxycholic acid on histologic progression in primary biliary cirrhosis.","volume":"39","author":"Poupon","year":"2003","journal-title":"J Hepatol"},{"key":"R13-4-20241201","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1002\/hep.510290603","article-title":"Tenyear survival in ursodeoxycholic acidtreated patients with primary biliary cirrhosis.","volume":"29","author":"Poupon","year":"1999","journal-title":"HEPATOLOGY"},{"key":"R14-4-20241201","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1053\/j.gastro.2004.11.009","article-title":"The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis.","volume":"128","author":"Corpechot","year":"2005","journal-title":"Gastroenterology"},{"key":"R15-4-20241201","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1023\/B:DDAS.0000037811.48575.da","article-title":"Survival of antimitochondrial antibodypositive and negative primary biliary cirrhosis patients on ursodeoxycholic acid treatment.","volume":"49","author":"Koulentaki","year":"2004","journal-title":"Dig Dis Sci"},{"key":"R16-4-20241201","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1365-2036.2005.02318.x","article-title":"Longterm ursodeoxycholic acid therapy for primary biliary cirrhosis: a followup to 12 years.","volume":"21","author":"Chan","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"key":"R17-4-20241201","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1111\/j.1572-0241.2006.00699.x","article-title":"Prognosis of ursodeoxycholic acidtreated patients with primary biliary cirrhosis. Results of a 10yr cohort study involving 297 patients.","volume":"101","author":"ter Borg","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"R18-4-20241201","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1053\/j.gastro.2005.12.029","article-title":"Excellent longterm survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic acid.","volume":"130","author":"Pares","year":"2006","journal-title":"Gastroenterology"},{"issue":"Suppl 1","key":"R19-4-20241201","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/S0168-8278(07)61709-7","article-title":"Biochemical response to UDCA and longterm risk of death or liver transplantation in PBC.","volume":"46","author":"Corpechot","year":"2007","journal-title":"J Hepatol"},{"key":"R20-4-20241201","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1053\/jhep.2001.20894","article-title":"Transplantation for primary biliary cirrhosis: retrospective analysis of 400 patients in a single center.","volume":"33","author":"Liermann Garcia","year":"2001","journal-title":"HEPATOLOGY"},{"key":"R21-4-20241201","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/hep.510300213","article-title":"Primary biliary cirrhosis once rare, now common in the United Kingdom?","volume":"30","author":"James","year":"1999","journal-title":"HEPATOLOGY"},{"issue":"Suppl","key":"R22-4-20241201","first-page":"A628","article-title":"Transplantation trends among primary biliary cirrhosis patients from 1995 to 2004. Abstract.","volume":"44","author":"Lee","year":"2006","journal-title":"HEPATOLOGY"},{"key":"R24-4-20241201","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1056\/NEJM199703063361003","article-title":"Ursodiol for primary sclerosing cholangitis.","volume":"336","author":"Lindor","year":"1997","journal-title":"N Engl J Med"},{"key":"R25-4-20241201","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1053\/j.gastro.2005.08.017","article-title":"Highdose ursodeoxycholic acid in primary sclerosing cholangitis: a 5year multicenter, randomized, controlled study.","volume":"129","author":"Olsson","year":"2005","journal-title":"Gastroenterology"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.21871","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-200710000-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T13:06:16Z","timestamp":1733058376000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-200710000-00004"}},"subtitle":["Bright and sunny around the Mediterranean but still cloudy and foggy in the United Kingdom"],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.21871","relation":{},"ISSN":["0270-9139"],"issn-type":[{"value":"0270-9139","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}