{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:13:05Z","timestamp":1790485985139,"version":"4.1.0"},"reference-count":3,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":167,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Hepatology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>\n                    Tenofovir disoproxil fumarate (TDF) is widely used as an effective first\u2010line therapy for chronic hepatitis B (CHB) infection. While TDF demonstrates successful viral suppression, it has been linked to the development of renal proximal tubular (PT) dysfunction, leading to Fanconi syndrome. However, Fanconi syndrome has been rarely reported in CHB\u2010monoinfected patients, and there were no reports of TDF\u2010associated nephrotic syndrome. Here, we report a case of combined Fanconi and nephrotic syndrome in CHB patients after TDF exposure. (H\n                    <jats:sc>epatology<\/jats:sc>\n                    2015;62:1318\u20101320)\n                  <\/jats:p>","DOI":"10.1002\/hep.27730","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T19:01:39Z","timestamp":1422644499000},"page":"1318-1320","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":31,"title":["Tenofovir\u2010associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection"],"prefix":"10.1097","volume":"62","author":[{"given":"Hyeon Seok","family":"Hwang","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol Whee","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong Jun","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Hepatology, Department of Internal Medicine, College of Medicine,The Catholic University of Korea,Seoul,Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2015,3,18]]},"reference":[{"key":"hep27730-bib-0001-20241017","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1517\/14740331003627458","article-title":"Renal toxicity associated with tenofovir use","volume":"9","year":"2010","journal-title":"Expert Opin Drug Saf"},{"key":"hep27730-bib-0002-20241017","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1038\/ki.2010.318","article-title":"Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities","volume":"78","year":"2010","journal-title":"Kidney Int"},{"key":"hep27730-bib-0003-20241017","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.semnephrol.2007.10.004","article-title":"Secondary IgA nephropathy","volume":"28","year":"2008","journal-title":"Semin Nephrol"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.27730","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-201510000-00036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T20:21:58Z","timestamp":1729196518000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-201510000-00036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,18]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.27730","relation":{},"ISSN":["0270-9139","1527-3350"],"issn-type":[{"value":"0270-9139","type":"print"},{"value":"1527-3350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,18]]},"assertion":[{"value":"2014-10-31","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-01-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}