{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:30:10Z","timestamp":1792467010261,"version":"4.5.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T00:00:00Z","timestamp":1553558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Hepatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>\n                    Improving care and treatment for persons infected with hepatitis C virus (HCV) can reduce HCV\u2010related morbidity and mortality. Our primary objective was to examine the HCV care continuum among patients receiving care at five federally qualified health centers (FQHCs) in Philadelphia, PA, where a testing and linkage to care program had been established. Among the five FQHCs, one served a homeless population, two served public housing residents, one served a majority Hispanic population, and the last, a \u201ctest and treat\u201d site, also provided HCV treatment to patients. We analyzed data from electronic health records of patients tested for HCV antibody from 2012 to 2016 and calculated the percentage of patients across nine steps of the HCV care continuum ranging from diagnosis to cure. We further explored factors associated with successful patient navigation through two steps of the continuum using multivariable logistic regression. Of 885 chronically infected patients, 92.2% received their RNA\u2010positive result, 82.7% were referred to an HCV provider, 69.4% were medically evaluated by the provider, 55.3% underwent liver disease staging, 15.0% initiated treatment, 12.0% completed treatment, 8.7% were assessed for sustained virologic response (SVR), and 8.0% achieved SVR. Regression results revealed that test and treat site patients were significantly more likely to be medically evaluated (adjusted odds ratio [aOR], 2.76; 95% confidence interval [CI], 1.82\u20104.17) and to undergo liver disease staging (aOR, 1.92; 95% CI, 1.02\u20102.86) than patients at the other FQHCs combined.\n                    <jats:italic toggle=\"yes\">Conclusion:<\/jats:italic>\n                    In this US urban setting, over two thirds of HCV\u2010infected patients were linked to care; although treatment uptake was low overall, it was highest at the test and treat site; scaling up treatment services in HCV testing settings will be vital to improve the HCV care continuum.\n                  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and Prevention,Atlanta,GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Bartholomew","sequence":"additional","affiliation":[{"name":"National Nurse\u2010Led Care Consortium,Philadelphia,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Klein","sequence":"additional","affiliation":[{"name":"Public Health Management Corporation,Philadelphia,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Kwakwa","sequence":"additional","affiliation":[{"name":"Philadelphia Department of Public Health,Philadelphia,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti H.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Epidemiology,Johns Hopkins Bloomberg School of Public Health,Baltimore,MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Holtzman","sequence":"additional","affiliation":[{"name":"Division of Viral 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