{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:35:32Z","timestamp":1789140932099,"version":"build-2803163510"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Hepatology"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1002\/hep.30649","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T15:01:05Z","timestamp":1554735665000},"page":"1056-1058","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":39,"title":["A Tale of Two Complications of Obesity: NASH and Hepatocellular Carcinoma"],"prefix":"10.1097","volume":"70","author":[{"given":"Renumathy","family":"Dhanasekaran","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology,Stanford University,Stanford,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean W.","family":"Felsher","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Departments of Medicine and Pathology,Stanford University,Stanford,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,5,27]]},"reference":[{"key":"hep30649-bib-0001-20241017","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1002\/hep.22734","article-title":"Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis","volume":"49","year":"2009","journal-title":"Hepatology"},{"key":"hep30649-bib-0002-20241017","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/apt.14937","article-title":"Systematic review with meta\u2010analysis: risk of hepatocellular carcinoma in non\u2010alcoholic steatohepatitis without cirrhosis compared to other liver diseases","volume":"48","year":"2018","journal-title":"Aliment Pharmacol Ther"},{"key":"hep30649-bib-0003-20241017","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.cell.2018.09.053","article-title":"Obesity drives STAT\u20101\u2010dependent NASH and STAT\u20103\u2010dependent HCC","volume":"175","year":"2018","journal-title":"Cell"},{"key":"hep30649-bib-0004-20241017","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.cmet.2014.05.011","article-title":"Hepatic oxidative stress promotes insulin\u2010STAT\u20105 signaling and obesity by inactivating protein tyrosine phosphatase N2","volume":"20","year":"2014","journal-title":"Cell Metab"},{"key":"hep30649-bib-0005-20241017","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1172\/JCI0215841","article-title":"Opposing roles of STAT1 and STAT3 in T cell\u2010mediated hepatitis: regulation by SOCS","volume":"110","year":"2002","journal-title":"J Clin Invest"},{"key":"hep30649-bib-0006-20241017","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1101\/gad.311852.118","article-title":"STAT3 is a master regulator of epithelial identity and KRAS\u2010driven tumorigenesis","volume":"32","year":"2018","journal-title":"Genes Dev"},{"key":"hep30649-bib-0007-20241017","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jhep.2017.10.006","article-title":"Should we undertake surveillance for HCC in patients with NAFLD?","volume":"68","year":"2018","journal-title":"J Hepatol"},{"key":"hep30649-bib-0008-20241017","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2147\/JHC.S159581","article-title":"Weighing the benefits of hepatocellular carcinoma surveillance against potential harms","volume":"6","year":"2019","journal-title":"J Hepatocell Carcinoma"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hep.30649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hep.30649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1002\/hep.30649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T00:17:42Z","timestamp":1729210662000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1002\/hep.30649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,27]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.30649","relation":{},"ISSN":["0270-9139","1527-3350"],"issn-type":[{"value":"0270-9139","type":"print"},{"value":"1527-3350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,27]]}}}