{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:24:29Z","timestamp":1765369469226,"version":"3.40.5"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T00:00:00Z","timestamp":1579824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T00:00:00Z","timestamp":1579824000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Hepatology"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n            <jats:title>Background and Aims<\/jats:title>\n            <jats:p>Human immunodeficiency virus (HIV)\u2013hepatitis C virus (HCV)\u2013coinfected patients are at high risk of metabolic complications and liver\u2010related events, which are both associated with hepatic steatosis and its progressive form, nonalcoholic steatohepatitis, a known risk factor for mortality. The fatty liver index (FLI), a noninvasive steatosis biomarker, has recently drawn attention for its clinical prognostic value, although its capacity to predict mortality risk in HIV\u2013HCV\u2010coinfected patients has never been investigated. Using a Cox proportional hazards model for mortality from all causes, with data from the French National Agency for Research on Aids and Viral Hepatitis CO13 HEPAVIH cohort (983 patients, 4,432 visits), we tested whether elevated FLI (\u226560) was associated with all\u2010cause mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Approach and Results<\/jats:title>\n            <jats:p>After multiple adjustment, individuals with FLI\u00a0\u2265\u00a060 had almost double the risk of all\u2010cause mortality (adjusted hazard ratio [95% confidence interval], 1.91 [1.17\u20103.12], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0=\u00a00.009), independently of the following factors: HCV cure (0.21 [0.07\u20100.61], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0=\u00a00.004), advanced fibrosis (1.77 [1.00\u20103.14], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0=\u00a00.05), history of hepatocellular carcinoma and\/or liver transplantation (7.74 [3.82\u201015.69], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0&lt;\u00a010<jats:sup>\u22123<\/jats:sup>), history of indirect clinical signs of cirrhosis (2.80 [1.22\u20106.41], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0=\u00a00.015), and HIV Centers for Disease Control and Prevention clinical stage C (2.88 [1.74\u20104.79], <jats:italic toggle=\"yes\">P<\/jats:italic>\u00a0&lt;\u00a010<jats:sup>\u22123<\/jats:sup>).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>An elevated FLI (\u226560) is a risk factor for all\u2010cause mortality in HIV\u2013HCV\u2010coinfected patients independently of liver fibrosis and HCV cure. In the present era of nearly 100% HCV cure rates thanks to direct\u2010acting antivirals, these findings encourage the more systematic use of noninvasive steatosis biomarkers to help identify coinfected patients with higher mortality risk.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.30914","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T22:43:43Z","timestamp":1567118623000},"page":"1182-1197","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Elevated Fatty Liver Index as a Risk Factor for All\u2010Cause Mortality in Human Immunodeficiency Virus\u2013Hepatitis C Virus\u2013Coinfected Patients (ANRS CO13 HEPAVIH Cohort Study)"],"prefix":"10.1097","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3439-8868","authenticated-orcid":false,"given":"Tangui","family":"Barr\u00e9","sequence":"first","affiliation":[{"name":"Aix Marseille Universit\u00e9,INSERM,IRD,SESSTIM,Sciences Economiques & Sociales de la Sant\u00e9 & Traitement de l\u2019Information M\u00e9dicale,Marseille,France"},{"name":"ORS PACA,Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d\u2019Azur,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camelia","family":"Protopopescu","sequence":"additional","affiliation":[{"name":"Aix Marseille Universit\u00e9,INSERM,IRD,SESSTIM,Sciences Economiques & Sociales de la Sant\u00e9 & Traitement de l\u2019Information M\u00e9dicale,Marseille,France"},{"name":"ORS PACA,Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d\u2019Azur,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firouz\u00e9","family":"Bani\u2010Sadr","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des Maladies Infectieuses et Tropicales,Centre Hospitalier Universitaire de Reims,H\u00f4pital Robert Debr\u00e9,Reims,France"},{"name":"Universit\u00e9 Reims Champagne Ardenne,EA\u20104684\/SFR CAP\u2010SANTE,Reims,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lionel","family":"Piroth","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'infectiologie,CHU de Dijon,Inserm CIC 1432,Universit\u00e9 de Bourgogne,Dijon,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1536-3675","authenticated-orcid":false,"given":"Teresa","family":"Rojas Rojas","sequence":"additional","affiliation":[{"name":"Aix Marseille Universit\u00e9,INSERM,IRD,SESSTIM,Sciences Economiques & Sociales de la Sant\u00e9 & Traitement de l\u2019Information M\u00e9dicale,Marseille,France"},{"name":"ORS PACA,Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d\u2019Azur,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Salmon\u2010Ceron","sequence":"additional","affiliation":[{"name":"Service Maladies Infectieuses et Tropicales,AP\u2010HP,H\u00f4pital Cochin,Paris,France"},{"name":"Universit\u00e9 Paris Descartes,Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Wittkop","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Bordeaux,ISPED,Inserm,Bordeaux Population Health Research Center,Team MORPH3EUS,UMR 1219,CIC\u2010EC 1401,Bordeaux,France"},{"name":"Service d\u2019information M\u00e9dicale,CHU de Bordeaux,P\u00f4le de sant\u00e9 publique,Bordeaux,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Esterle","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Bordeaux,ISPED,Inserm,Bordeaux Population Health Research Center,Team MORPH3EUS,UMR 1219,CIC\u2010EC 1401,Bordeaux,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Sogni","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Descartes,Paris,France"},{"name":"INSERM U1223,Institut Pasteur,Paris,France"},{"name":"Service d\u2019H\u00e9patologie,AP\u2010HP,H\u00f4pital Cochin,Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine","family":"Lacombe","sequence":"additional","affiliation":[{"name":"Department of Infectious and Tropical Diseases,Saint\u2010Antoine Hospital,AP\u2010HP,Paris,France"},{"name":"Sorbonne Universit\u00e9s,INSERM,UPMC Universit\u00e9 de Paris 06,Institut Pierre Louis d\u2019\u00e9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP UMRS 1136),Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Chas","sequence":"additional","affiliation":[{"name":"Service Maladies Infectieuses et Tropicales,Assistance Publique des H\u00f4pitaux de Paris,H\u00f4pital Tenon,Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Zaegel","sequence":"additional","affiliation":[{"name":"Service d\u2019Immuno\u2010H\u00e9matologie Clinique,Aix\u2010Marseille Universit\u00e9,APHM Sainte\u2010Marguerite,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Laure","family":"Chaix","sequence":"additional","affiliation":[{"name":"Department of Virology,National Reference Centre for HIV,Denis Diderot\u2013Paris 7 University,INSERM U941,APHP, Saint\u2010Louis Hospital,Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Miailhes","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales,Hospices Civils de Lyon,H\u00f4pital de la Croix Rousse,Lyon,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Serfaty","sequence":"additional","affiliation":[{"name":"Service d\u2019H\u00e9pato\u2010gastroent\u00e9rologie,H\u00f4pital Hautepierre,H\u00f4pitaux Universitaires de Strasbourg,INSERM UMR 938,Universit\u00e9 Paris Sorbonne,Paris,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8853-3829","authenticated-orcid":false,"given":"Fabienne","family":"Marcellin","sequence":"additional","affiliation":[{"name":"Aix Marseille Universit\u00e9,INSERM,IRD,SESSTIM,Sciences Economiques & Sociales de la Sant\u00e9 & Traitement de l\u2019Information M\u00e9dicale,Marseille,France"},{"name":"ORS PACA,Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d\u2019Azur,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6794-4837","authenticated-orcid":false,"given":"Maria Patrizia","family":"Carrieri","sequence":"additional","affiliation":[{"name":"Aix Marseille Universit\u00e9,INSERM,IRD,SESSTIM,Sciences Economiques & Sociales de la Sant\u00e9 & Traitement de l\u2019Information M\u00e9dicale,Marseille,France"},{"name":"ORS PACA,Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d\u2019Azur,Marseille,France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"ANRS CO13 HEPAVIH Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2020,1,24]]},"reference":[{"journal-title":"PLoS ONE","article-title":"Prevalence and determinants of non\u2010alcoholic fatty liver disease in lifelines: a large Dutch population cohort","year":"2017","key":"hep30914-bib-0001-20241017"},{"key":"hep30914-bib-0002-20241017","first-page":"190","article-title":"Non\u2010alcoholic fatty liver disease and HIV\/AIDS: a new way of modulation of cardiovascular risk","volume":"19","year":"2017","journal-title":"AIDS Rev"},{"key":"hep30914-bib-0003-20241017","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.cld.2017.03.004","article-title":"Metabolic manifestations of hepatitis C virus: diabetes mellitus, dyslipidemia","volume":"21","year":"2017","journal-title":"Clin Liver Dis"},{"key":"hep30914-bib-0004-20241017","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/hep.23619","article-title":"Hepatic steatosis in patients coinfected with human immunodeficiency virus\/hepatitis C virus: a meta\u2010analysis of the risk factors","volume":"52","year":"2010","journal-title":"Hepatology"},{"key":"hep30914-bib-0005-20241017","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.atherosclerosis.2012.01.051","article-title":"Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV\u2010related steatosis","volume":"221","year":"2012","journal-title":"Atherosclerosis"},{"key":"hep30914-bib-0006-20241017","doi-asserted-by":"crossref","first-page":"e397","DOI":"10.1016\/j.ijid.2012.01.011","article-title":"Prospective evaluation of hepatic steatosis in HIV\u2010infected patients with or without hepatitis C virus coinfection","volume":"16","year":"2012","journal-title":"Int J Infect Dis"},{"key":"hep30914-bib-0007-20241017","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3390\/ijms17050717","article-title":"Non\u2010alcoholic fatty liver disease and extra\u2010hepatic cancers","volume":"17","year":"2016","journal-title":"Int J Mol Sci"},{"key":"hep30914-bib-0008-20241017","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.metabol.2015.12.012","article-title":"The multiple\u2010hit pathogenesis of non\u2010alcoholic fatty liver disease (NAFLD)","volume":"65","year":"2016","journal-title":"Metabolism"},{"key":"hep30914-bib-0009-20241017","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.jhep.2006.02.009","article-title":"Impact of human immunodeficiency virus infection on the prevalence and severity of steatosis in patients with chronic hepatitis C virus infection","volume":"44","year":"2006","journal-title":"J Hepatol"},{"key":"hep30914-bib-0010-20241017","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/01.aids.0000163935.99401.25","article-title":"Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus","volume":"19","year":"2005","journal-title":"AIDS"},{"key":"hep30914-bib-0011-20241017","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1086\/505495","article-title":"Hepatic steatosis is associated with fibrosis, nucleoside analogue use, and hepatitis C virus genotype 3 infection in HIV\u2010seropositive patients","volume":"43","year":"2006","journal-title":"Clin Infect Dis"},{"key":"hep30914-bib-0012-20241017","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1089\/aid.2016.0051","article-title":"The risk of cardiovascular disease, diabetes, liver\u2010related outcomes, and death over 10 years in HIV\/HCV\u2010coinfected patients with and without steatosis","volume":"32","year":"2016","journal-title":"AIDS Res Hum Retroviruses"},{"key":"hep30914-bib-0013-20241017","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.jhep.2015.11.004","article-title":"EASL\u2010EASD\u2010EASO Clinical practice guidelines for the management of non\u2010alcoholic fatty liver disease","volume":"64","year":"2016","journal-title":"J Hepatol"},{"key":"hep30914-bib-0014-20241017","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/hep.24356","article-title":"Fatty liver index and mortality: the Cremona study in the 15th year of follow\u2010up","volume":"54","year":"2011","journal-title":"Hepatology"},{"key":"hep30914-bib-0015-20241017","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.numecd.2013.02.004","article-title":"The fatty liver index is associated with increased mortality in subjects referred to coronary angiography","volume":"23","year":"2013","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"hep30914-bib-0016-20241017","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/1471-2334-10-303","article-title":"The French national prospective cohort of patients coinfected with HIV and HCV (ANRS CO13 HEPAVIH): early findings, 2006\u20102010","volume":"10","year":"2010","journal-title":"BMC Infect Dis"},{"key":"hep30914-bib-0017-20241017","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00042560-200111010-00005","article-title":"The dynamic of adherence to highly active antiretroviral therapy: results from the French National APROCO cohort","volume":"28","year":"2001","journal-title":"J Acquir Immune Defic Syndr"},{"key":"hep30914-bib-0018-20241017","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1017\/S0767399X00001590","article-title":"La version fran\u00e7aise de l\u2019\u00e9chelle CES\u2010D (Center for Epidemiologic Studies\u2010Depression Scale). Description et traduction de l\u2019\u00e9chelle d\u2019auto\u00e9valuation","volume":"4","year":"1989","journal-title":"Psychiatr Psychobiol"},{"key":"hep30914-bib-0019-20241017","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1001\/archinte.158.16.1789","article-title":"The AUDIT alcohol consumption questions (AUDIT\u2010C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test","volume":"158","year":"1998","journal-title":"Arch Intern Med"},{"key":"hep30914-bib-0020-20241017","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-230X-6-33","article-title":"The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population","volume":"6","year":"2006","journal-title":"BMC Gastroenterol"},{"key":"hep30914-bib-0021-20241017","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.jhep.2017.08.005","article-title":"Protective effect of coffee consumption on all\u2010cause mortality of French HIV\u2010HCV coinfected patients","volume":"67","year":"2017","journal-title":"J Hepatol"},{"key":"hep30914-bib-0022-20241017","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1136\/bmj.284.6314.495","article-title":"ABC of alcohol. Help: referral","volume":"284","year":"1982","journal-title":"Br Med J (Clin Res Ed)"},{"key":"hep30914-bib-0023-20241017","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/hep.21178","article-title":"Development of a simple noninvasive index to predict significant fibrosis in patients with HIV\/HCV coinfection","volume":"43","year":"2006","journal-title":"Hepatology"},{"key":"hep30914-bib-0024-20241017","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/biomet\/81.3.515","article-title":"Proportional hazards tests and diagnostics based on weighted residuals","volume":"81","year":"1994","journal-title":"Biometrika"},{"key":"hep30914-bib-0025-20241017","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1530\/EJE-14-0112","article-title":"External validation of the fatty liver index and lipid accumulation product indices, using 1H\u2010magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin\u2010resistant individuals","volume":"171","year":"2014","journal-title":"Eur J Endocrinol"},{"key":"hep30914-bib-0026-20241017","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1097\/QAD.0000000000001504","article-title":"Prevalence and risk factors of nonalcoholic fatty liver disease in HIV\u2010monoinfection","volume":"31","year":"2017","journal-title":"AIDS"},{"key":"hep30914-bib-0027-20241017","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.jhep.2008.01.015","article-title":"Hepatic steatosis in HIV\/HCV coinfected patients: correlates, efficacy and outcomes of anti\u2010HCV therapy: a paired liver biopsy study","volume":"48","year":"2008","journal-title":"J Hepatol"},{"key":"hep30914-bib-0028-20241017","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/hep.23521","article-title":"Long\u2010term mortality in NAFLD: is liver histology of any prognostic significance?","volume":"51","year":"2010","journal-title":"Hepatology"},{"key":"hep30914-bib-0029-20241017","doi-asserted-by":"crossref","first-page":"d6891","DOI":"10.1136\/bmj.d6891","article-title":"Non\u2010alcoholic fatty liver disease and mortality among US adults: prospective cohort study","volume":"343","year":"2011","journal-title":"BMJ"},{"key":"hep30914-bib-0030-20241017","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1002\/hep.28390","article-title":"Noninvasive fatty liver markers predict liver disease mortality in the U.S. population","volume":"63","year":"2016","journal-title":"Hepatology"},{"key":"hep30914-bib-0031-20241017","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.jhep.2005.01.022","article-title":"Liver disease as a major cause of death among HIV infected patients: role of hepatitis C and B viruses and alcohol","volume":"42","year":"2005","journal-title":"J Hepatol"},{"issue":"Suppl. 1","key":"hep30914-bib-0032-20241017","first-page":"S13","article-title":"Pathogenesis of accelerated fibrosis in HIV\/HCV co\u2010infection","volume":"207","year":"2013","journal-title":"J Infect Dis"},{"key":"hep30914-bib-0033-20241017","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1086\/527565","article-title":"Progression of fibrosis in HIV and hepatitis C virus\u2013coinfected patients treated with interferon plus ribavirin\u2010based therapy: analysis of risk factors","volume":"46","year":"2008","journal-title":"Clin Infect Dis"},{"key":"hep30914-bib-0034-20241017","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1086\/367643","article-title":"Progression of chronic hepatitis C to liver fibrosis and cirrhosis in patients coinfected with hepatitis C virus and human immunodeficiency virus","volume":"36","year":"2003","journal-title":"Clin Infect Dis"},{"key":"hep30914-bib-0035-20241017","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1111\/j.1365-2036.2007.03533.x","article-title":"Hepatic steatosis in HIV\u2010HCV coinfected patients in France: comparison with HCV monoinfected patients matched for body mass index and HCV genotype","volume":"26","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"hep30914-bib-0036-20241017","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1093\/cid\/civ396","article-title":"Long\u2010term treatment outcomes of patients infected with hepatitis C virus: a systematic review and meta\u2010analysis of the survival benefit of achieving a sustained virological response","volume":"61","year":"2015","journal-title":"Clin Infect Dis"},{"key":"hep30914-bib-0037-20241017","doi-asserted-by":"crossref","first-page":"32","DOI":"10.5582\/bst.2018.01299","article-title":"Fibrosis\u20104 index predicts mortality in HIV\/HCV coinfected patients receiving combination antiretroviral therapy in rural China","volume":"13","year":"2019","journal-title":"Biosci Trends"},{"key":"hep30914-bib-0038-20241017","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1038\/ajg.2009.746","article-title":"Noninvasive markers of liver fibrosis are highly predictive of liver\u2010related death in a cohort of HCV\u2010infected individuals with and without HIV infection","volume":"105","year":"2010","journal-title":"Am J Gastroenterol"},{"issue":"Suppl. 1","key":"hep30914-bib-0039-20241017","first-page":"13","article-title":"Impact of hepatitis C virus therapy on metabolism and public health","volume":"37","year":"2017","journal-title":"Liver Int"},{"key":"hep30914-bib-0040-20241017","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s11904-016-0330-z","article-title":"Metabolic complications and glucose metabolism in HIV infection: a review of the evidence","volume":"13","year":"2016","journal-title":"Curr HIV\/AIDS Rep"},{"key":"hep30914-bib-0041-20241017","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1111\/jvh.12725","article-title":"HIV\/HCV coinfection and the risk of cardiovascular disease: a meta\u2010analysis","volume":"24","year":"2017","journal-title":"J Viral Hepat"},{"key":"hep30914-bib-0042-20241017","article-title":"Non\u2010alcoholic fatty liver disease, liver biomarkers and stroke risk: the Reasons for Geographic and Racial Differences in Stroke cohort","volume":"13","year":"2018","journal-title":"PLoS ONE"},{"key":"hep30914-bib-0043-20241017","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1002\/hep.22845","article-title":"Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population","volume":"49","year":"2009","journal-title":"Hepatology"},{"key":"hep30914-bib-0044-20241017","first-page":"e307","article-title":"Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV\/HCV\u2010coinfected patients","volume":"18","year":"2011","journal-title":"J Viral Hepat"},{"key":"hep30914-bib-0045-20241017","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.diabres.2018.05.024","article-title":"Metabolic syndrome and cancer: \u201cthe common soil hypothesis\u201d","volume":"143","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"key":"hep30914-bib-0046-20241017","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00146266","article-title":"Unexpected effects of coffee consumption on liver enzymes","volume":"9","year":"1993","journal-title":"Eur J Epidemiol"},{"key":"hep30914-bib-0047-20241017","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.3390\/nu11061274","article-title":"Coffee intake and obesity: a meta\u2010analysis","volume":"11","year":"2019","journal-title":"Nutrients"},{"key":"hep30914-bib-0048-20241017","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.maturitas.2012.08.007","article-title":"Marital status, health and mortality","volume":"73","year":"2012","journal-title":"Maturitas"},{"key":"hep30914-bib-0050-20241017","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1097\/QAD.0000000000000377","article-title":"Mortality in HIV\u2010hepatitis C coinfected patients in Canada compared to the general Canadian population (2003\u20102013)","volume":"28","year":"2014","journal-title":"AIDS"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hep.30914","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hep.30914","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1002\/hep.30914","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T00:03:30Z","timestamp":1729209810000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1002\/hep.30914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,24]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.30914","relation":{},"ISSN":["0270-9139","1527-3350"],"issn-type":[{"type":"print","value":"0270-9139"},{"type":"electronic","value":"1527-3350"}],"subject":[],"published":{"date-parts":[[2020,1,24]]},"assertion":[{"value":"2019-03-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-15","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}