{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:20:27Z","timestamp":1790367627602,"version":"4.1.0"},"reference-count":165,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>In selected patients with cirrhosis and ascites, transjugular intrahepatic portosystemic shunt (TIPS) placement improves control of ascites and may reduce mortality. In this review, we summarize the current knowledge concerning the use of TIPS for the treatment of ascites in patients with cirrhosis, from pathophysiology of ascites formation to hemodynamic consequences, patient selection, and technical issues of TIPS insertion. The combination of these factors is important to guide clinical decision\u2010making and identify the best strategy for each individual patient. There is still a need to identify the best timing for TIPS placement in the natural history of ascites (recurrent vs. refractory) as well as which type and level of renal dysfunction is acceptable when TIPS is proposed for the treatment of ascites in cirrhosis. Future studies are needed to define the optimal stent diameter according to patient characteristics and individual risk of shunt\u2010related side effects, particularly hepatic encephalopathy and insufficient cardiac response to hemodynamic consequences of TIPS insertion.<\/jats:p>","DOI":"10.1002\/hep.32596","type":"journal-article","created":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T03:45:29Z","timestamp":1654314329000},"page":"640-658","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":67,"title":["The role of transjugular intrahepatic portosystemic shunt in patients with cirrhosis and ascites: Recent evolution and open questions"],"prefix":"10.1097","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4253-6028","authenticated-orcid":false,"given":"Pierre","family":"Deltenre","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"},{"name":"Department of Gastroenterology and Hepatology, CHU UCL Namur, Universit\u00e9 Catholique de Louvain, Yvoir, Belgium"},{"name":"Department of Gastroenterology and Hepatology, Clinique St Luc, Bouge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6734-7178","authenticated-orcid":false,"given":"Alberto","family":"Zanetto","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatic Hemodynamic Laboratory, Azienda Ospedaliero\u2010Universitaria di Modena, and University of Modena and Reggio Emilia, Modena, Italy"},{"name":"Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology, and Gastroenterology, Padova University Hospital, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Saltini","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatic Hemodynamic Laboratory, Azienda Ospedaliero\u2010Universitaria di Modena, and University of Modena and Reggio Emilia, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Moreno","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"},{"name":"Laboratory of Experimental Gastroenterology, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Schepis","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatic Hemodynamic Laboratory, Azienda Ospedaliero\u2010Universitaria di Modena, and University of Modena and Reggio Emilia, Modena, 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