{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T23:31:39Z","timestamp":1780529499321,"version":"3.54.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":7031,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1996,6]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>\n                                 <jats:bold>Our goal was to determine a subset of patients at high risk of developing liver abscesses after local treatment of liver tumors (LTLT) and establish guidelines for the conduct of LTLT in the safest conditions in such patients. Five hundred sixty\u2013one LTLT, 489 transhepatic arterial chemoembolizations (TAC, 10 hepatic embolizations, and 62 percutaneous intratumor injections (PIT), were retrospectively reviewed for liver parenchyma necrosis and abscess formation. Four patients developed abscesses, three after TAC and one after PIT. Despite broad\u2013spectrum antibiotherapy, percutaneous drainage, and surgery, two patients died. A left hepatectomy was required in the other two patients for cure. All four patients had a carcinoid or a neuroendocrine pancreatic tumor. Three out of four patients had bilioenteric anastomoses, and the fourth had recently undergone cholecystectomy and papillotomy. A Lipiodol\/doxorubicin mixture without any particulate embolization was injected in the three patients who developed abscesses after TAC. LTLT in patients with bilio enteric anastomosis or papillotomy and\/or neuroendocrine or carcinoid tumor should be performed with strict precautions during the procedure and for peri\u2013procedural care.<\/jats:bold>\n                              <\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.510230620","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T00:08:12Z","timestamp":1100218092000},"page":"1436-1440","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":93,"title":["Liver Abscess Formation After Local Treatment of Liver Tumors"],"prefix":"10.1097","volume":"23","author":[{"given":"T","family":"de Ba\u00e8re","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Roche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Amenabar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Lagrange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Ducreux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Rougier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Elias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Lasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Patriarche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"10.1002\/hep.510230620-BIB1|cit1","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1055\/s-2008-1074718","article-title":"Chemoembolization of liver tumors","volume":"10","author":"Charnsangavej","year":"1993","journal-title":"Semin Intervent Radiol"},{"key":"10.1002\/hep.510230620-BIB2|cit2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1002\/jcu.1870210811","article-title":"Abscess formation in hepatocellular carcinoma: complications of percutaneous ultrasound-guided ethanol injection","volume":"21","author":"Solinas","year":"1993","journal-title":"J Clin Ultrasound"},{"key":"10.1002\/hep.510230620-BIB3|cit3","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1051-0443(94)71504-9","article-title":"Prevalence of infection following hepatic chemoembolization with cross-linked collagen with administration of prophylactic antibiotics","volume":"5","author":"Reed","year":"1994","journal-title":"J Vasc Intervent Radiol"},{"key":"10.1002\/hep.510230620-BIB4|cit4","first-page":"2505","article-title":"Transarterial chem-oembolisation in metastatic liver tumor after curative resection of pancreatic cancer","volume":"15","author":"Ishikawa","year":"1988","journal-title":"Jpn J Cancer Chemother"},{"key":"10.1002\/hep.510230620-BIB5|cit5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1051-0443(94)71477-9","article-title":"Clostridial bacteremia and death following chemoembolization for hepatocellular carcinoma","volume":"5","author":"Gerson","year":"1994","journal-title":"J Vasc Interv Radiol"},{"key":"10.1002\/hep.510230620-BIB6|cit6","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1055\/s-2008-1074753","article-title":"Complications of hepatic arterial embolization and chemoembolization Treatment and prevention","volume":"11","author":"Chuang","year":"1994","journal-title":"Semin Interventional Radiol"},{"key":"10.1002\/hep.510230620-BIB7|cit7","first-page":"496","article-title":"Liver abscess after percutaneous ethanol injection therapy for hepatocellular carcinoma. 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