{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T06:40:01Z","timestamp":1791614401545,"version":"4.3.4"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatol Commun"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>Accurate population\u2010based data are needed on the rate, economic impact, and the long<jats:bold>\u2010<\/jats:bold>term outcomes of readmission among patients with cirrhosis. To examine the rates, costs, and 1\u2010year outcomes of patients readmitted within 30 days following their index hospitalization for complications of cirrhosis, we conducted a nationwide, population\u2010based cohort study involving all patients with cirrhosis in Thailand from 2009 through 2013, using data from the National Health Security Office databases, which included those from nationwide hospitalizations. Readmission was captured from hospitals at all health care levels across the country within the Universal Coverage Scheme. For the 134,038 patients hospitalized with cirrhosis, the overall 30\u2010day readmission rate was 17%. Common causes of readmission consisted of complications of portal hypertension (47%) and infections (17%). After adjusting for multiple covariates, predictors of 30\u2010day readmission included hepatocellular carcinoma (odds ratio [OR] 1.95, 95% confidence interval [CI] 1.84\u20102.06), human immunodeficiency virus\u2013related admission (OR 1.81, 95% CI 1.51\u20102.17) and cholangiocarcinoma (OR 1.64, 95% CI 1.3\u20102.05). In all, 2,936 deaths (13%) occurred during readmission, and an additional 14,425 deaths up to 1 year (63.5% total mortality among readmitted patients). Causes of death were mostly from liver\u2010related mortality. Average cost at index admission for those with a 30\u2010day readmission were significantly higher than those readmitted beyond 30 days or not readmitted. <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic> Patients hospitalized with cirrhosis complications had high rates of unscheduled 30\u2010day readmission. Average hospitalization costs were high, and only 36.5% of patients readmitted within 30 days survived at 1 year.<\/jats:p>","DOI":"10.1002\/hep4.1472","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T15:17:43Z","timestamp":1579619863000},"page":"453-460","source":"Crossref","is-referenced-by-count":34,"title":["Thirty\u2010Day Readmission and Cost Analysis in Patients With Cirrhosis: A Nationwide Population\u2010Based Data"],"prefix":"10.1097","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6924-8504","authenticated-orcid":false,"given":"Sakkarin","family":"Chirapongsathorn","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology,Department of Medicine,Phramongkutklao Hospital,College of Medicine, Royal Thai Army,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kittiyod","family":"Poovorawan","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine,Faculty of Tropical Medicine,Mahidol University,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngamphol","family":"Soonthornworasiri","sequence":"additional","affiliation":[{"name":"Department of Tropical Hygiene,Faculty of Tropical Medicine,Mahidol University,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wirichada","family":"Pan\u2010ngum","sequence":"additional","affiliation":[{"name":"Department of Tropical Hygiene,Faculty of Tropical Medicine,Mahidol University,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamthorn","family":"Phaosawasdi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology,Vichaiyut Hospital,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sombat","family":"Treeprasertsuk","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology,Department of Medicine,Chulalongkorn University,Bangkok,Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"hep41472-bib-0001-20240114","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s12916-014-0145-y","article-title":"Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis","volume":"12","year":"2014","journal-title":"BMC Med"},{"key":"hep41472-bib-0002-20240114","first-page":"661","article-title":"The current economic burden of cirrhosis","volume":"7","year":"2011","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"hep41472-bib-0003-20240114","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1111\/jgh.13928","article-title":"Adding C\u2010reactive protein and procalcitonin to the model of end\u2010stage liver disease score improves mortality prediction in patients with complications of cirrhosis","volume":"33","year":"2018","journal-title":"J Gastroenterol 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