{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T08:22:51Z","timestamp":1781598171128,"version":"3.54.5"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Hepatol Commun"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>High\u2010grade portal vein thrombosis (PVT) is often considered to be a technically challenging scenario for liver transplantation (LT) and in some centers a relative contraindication. This study compares patients with chronic obliterative PVT who underwent portal vein recanalization\u2013transjugular intrahepatic portosystemic shunt (PVR\u2010TIPS) and subsequent LT to those with partial nonocclusive PVT who underwent LT without an intervention. This institutional review board\u2010approved study analyzed 49 patients with cirrhosis with PVT from 2000 to 2020 at our institution. Patients were divided into two groups, those that received PVR\u2010TIPS due to anticipated surgical challenges from chronic obliterative PVT and those who did not because of partial PVT. Demographic data and long\u2010term outcomes were compared. A total of 35 patients received PVR\u2010TIPS while 14 did not, with all receiving LT. Patients with PVR\u2010TIPS had a higher Yerdel score and frequency of cavernoma than those that did not. PVR\u2010TIPS was effective in decreasing portosystemic gradient (16 down to 8\u00a0mm HG; <jats:italic toggle=\"yes\">p<\/jats:italic> &lt;\u00a00.05). Both groups allowed for end\u2010to\u2010end anastomoses in &gt;90% of cases. However, veno\u2013veno bypass was used significantly more in patients who did not receive PVR\u2010TIPS. Additionally, patients without PVR\u2010TIPS required significantly more intraoperative red blood cells. Overall survival was not different between groups. PVR\u2010TIPS demonstrated efficacy in resolving PVT and allowed for end\u2010to\u2010end portal vein anastomoses. PVR\u2010TIPS is a viable treatment option for chronic obliterative PVT with or without cavernoma that simplifies the surgical aspects of LT.<\/jats:p>","DOI":"10.1002\/hep4.1914","type":"journal-article","created":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T18:09:43Z","timestamp":1645985383000},"page":"1803-1812","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":24,"title":["Preoperative portal vein recanalization\u2013transjugular intrahepatic portosystemic shunt for chronic obliterative portal vein thrombosis: Outcomes following liver transplantation"],"prefix":"10.1097","volume":"6","author":[{"given":"Abhinav","family":"Talwar","sequence":"first","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel M.","family":"Knight","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Katariya","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan\u2010Carlos","family":"Caicedo","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zach","family":"Dietch","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Borja\u2010Cacho","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5526-8272","authenticated-orcid":false,"given":"Daniella","family":"Ladner","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick","family":"Christopher","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talia","family":"Baker","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,University of Chicago,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Abecassis","sequence":"additional","affiliation":[{"name":"Department of Surgery,Division of Transplant Surgery,University of Arizona,Tucson,Arizona,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samdeep","family":"Mouli","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kush","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahsun","family":"Riaz","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Thornburg","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9745-1825","authenticated-orcid":false,"given":"Riad","family":"Salem","sequence":"additional","affiliation":[{"name":"Department of Radiology,Section of Vascular and Interventional Radiology,Northwestern University,Chicago,Illinois,USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,2,27]]},"reference":[{"key":"hep41914-bib-0001-20241115","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jhep.2004.01.001","article-title":"Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis","volume":"40","year":"2004","journal-title":"J Hepatol"},{"key":"hep41914-bib-0002-20241115","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1002\/lt.25462","article-title":"Expanding the donor pool with the use of extended criteria donation after 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