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Hippocampal volume reduction is now one of the most consistent structural abnormalities found in schizophrenia: it is present at the onset of the illness and, to a lesser degree, in first\u2010degree relatives of schizophrenic probands. Decreased levels of N\u2010acetyl\u2010aspartate point towards a cellular basis of such volume changes. Functional neuroimaging studies have demonstrated abnormal levels of hippocampal activity at rest, during the experience of auditory hallucinations, and during the performance of memory retrieval tasks. These results of neuroimaging studies complement evidence from post\u2010mortem and behavioral studies, which have found regionally specific abnormalities of the hippocampus and of memory function in schizophrenia. Hippocampus 2001;11:520\u2013528. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/hipo.1068","type":"journal-article","created":{"date-parts":[[2004,11,14]],"date-time":"2004-11-14T11:43:44Z","timestamp":1100432624000},"page":"520-528","source":"Crossref","is-referenced-by-count":338,"title":["Neuroimaging studies of the hippocampus in schizophrenia"],"prefix":"10.1002","volume":"11","author":[{"given":"Stephan","family":"Heckers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/17.1.19"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000228852"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-547625-6.50026-X"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00152-3"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.9.3.460"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/oso\/9780192629074.003.0003","volume-title":"The neuropathology of schizophrenia. 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