{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:18:19Z","timestamp":1791404299379,"version":"4.3.3"},"reference-count":52,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T00:00:00Z","timestamp":1392076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hippocampus"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Declarative memory refers to a spatial strategy using numerous sources of sensory input information in which visual and vestibular inputs are assimilated in the hippocampus. In contrast, procedural memory refers to a response strategy based on motor skills and familiar gestures and involves the striatum. Even if vestibular loss impairs hippocampal activity and spatial memory, vestibular\u2010lesioned rats remain able to find food rewards during complex spatial memory task. Since hippocampal lesions induce a switch from declarative memory to procedural memory, we hypothesize that vestibular\u2010lesioned rats use a strategy other than that of hippocampal spatial response to complete the task and to counterbalance the loss of vestibular information. We test, in a reverse T\u2010maze paradigm, the types of strategy vestibular\u2010lesioned rats preferentially uses in a spatial task. We clearly demonstrate that all vestibular\u2010lesioned rats shift to a response strategy to solve the spatial task, while control rats use spatial and response strategies equally. We conclude that the loss of vestibular informations leading to spatial learning impairments is not offset at the hippocampus level by integration process of other sense mainly visual informations; but favors a response strategy through procedural memory most likely involving the striatum, cerebellum, and motor learning. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/hipo.22251","type":"journal-article","created":{"date-parts":[[2014,1,27]],"date-time":"2014-01-27T05:48:41Z","timestamp":1390801721000},"page":"591-597","source":"Crossref","is-referenced-by-count":25,"title":["Vestibular loss promotes procedural response during a spatial task in rats"],"prefix":"10.1002","volume":"24","author":[{"given":"Marie\u2010Laure","family":"Machado","sequence":"first","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Lelong\u2010Boulouard","sequence":"additional","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"},{"name":"CHU de Caen, Department of Pharmacology Caen CS 30001 14033 CEDEX 9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Philoxene","sequence":"additional","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Davis","sequence":"additional","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Denise","sequence":"additional","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"},{"name":"CHU de Caen, Department of Functional Exploration Caen CS 30001 14033 CEDEX 9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Besnard","sequence":"additional","affiliation":[{"name":"Normandie University  France"},{"name":"UNICAEN, COMETE Caen 14032 France"},{"name":"Inserm, U 1075 COMETE Caen 14032 France"},{"name":"CHU de Caen, Department of Functional Exploration Caen CS 30001 14033 CEDEX 9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(07)00006-4"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00147.2005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn951"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2010.08.007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-15-06304.2003"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.3.472"},{"issue":"1","key":"e_1_2_6_8_1","first-page":"58","article-title":"Synaptic plasticity and the neurobiology of learning and memory","volume":"78","author":"Benfenati F","year":"2007","journal-title":"Acta Biomed"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20942"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi314"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90400-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh617"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1440.002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(03)00063-9"},{"key":"e_1_2_6_15_1","first-page":"83","volume-title":"Neuropsychology of Memory","author":"Cohen NJ","year":"1984"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2004.07.003"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"6183","DOI":"10.1523\/JNEUROSCI.19-14-06183.1999","article-title":"Differential activation of adenylyl cyclases by spatial and procedural learning","volume":"19","author":"Guillou JL","year":"1999","journal-title":"J Neurosci"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20283"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00229361"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5280.1399"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb09188.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.119.4.853"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00878-3"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2012.06.016"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.05.029"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.450050305"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7427(02)00014-X"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80987-3"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/319774a0"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2002.02100.x"},{"key":"e_1_2_6_31_1","volume-title":"The Hippocampus as a Cognitive Map","author":"O'Keefe J","year":"1978"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(01)00280-X"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.09-05-01465.1989"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1006\/nlme.1996.0007"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00813-4"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-2003-13102"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-16-06490.2003"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00953.2005"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2006.08.014"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/35102568"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20588"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2004.06.005"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(84)90057-5"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.1112"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(01)00270-4"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.24.13438"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2011.10.008"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-22-10009.2002"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(97)80004-9"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20266"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20533"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054527"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22063"}],"container-title":["Hippocampus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhipo.22251","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.22251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T13:26:16Z","timestamp":1696339576000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hipo.22251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,11]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1002\/hipo.22251"],"URL":"https:\/\/doi.org\/10.1002\/hipo.22251","archive":["Portico"],"relation":{},"ISSN":["1050-9631","1098-1063"],"issn-type":[{"value":"1050-9631","type":"print"},{"value":"1098-1063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,11]]}}}