{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:03:06Z","timestamp":1792414986206,"version":"4.4.0"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T00:00:00Z","timestamp":1411603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000854","name":"Human Frontier Science Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000324","name":"Gatsby Charitable Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000324","id-type":"DOI","asserted-by":"publisher"}]},{"name":"EU FP7 Spacebrain"},{"name":"Foundation Adelis"},{"DOI":"10.13039\/501100003977","name":"Israeli Science Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hippocampus"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Rodent hippocampus exhibits strikingly different regimes of population activity in different behavioral states. During locomotion, hippocampal activity oscillates at theta frequency (5\u201312 Hz) and cells fire at specific locations in the environment, the place fields. As the animal runs through a place field, spikes are emitted at progressively earlier phases of the theta cycles. During immobility, hippocampus exhibits sharp irregular bursts of activity, with occasional rapid orderly activation of place cells expressing a possible trajectory of the animal. The mechanisms underlying this rich repertoire of dynamics are still unclear. We developed a novel recurrent network model that accounts for the observed phenomena. We assume that the network stores a map of the environment in its recurrent connections, which are endowed with short\u2010term synaptic depression. We show that the network dynamics exhibits two different regimes that are similar to the experimentally observed population activity states in the hippocampus. The operating regime can be solely controlled by external inputs. Our results suggest that short\u2010term synaptic plasticity is a potential mechanism contributing to shape the population activity in hippocampus. \u00a9 2014 The Authors. Hippocampus Published by Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/hipo.22355","type":"journal-article","created":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T09:20:15Z","timestamp":1408958415000},"page":"94-105","source":"Crossref","is-referenced-by-count":103,"title":["Short\u2010term plasticity based network model of place cells dynamics"],"prefix":"10.1002","volume":"25","author":[{"given":"Sandro","family":"Romani","sequence":"first","affiliation":[{"name":"Department of Neurobiology Weizmann Institute of Science Rehovot 76100 Israel"},{"name":"Department of Neuroscience, Center for Theoretical Neuroscience College of Physicians and Surgeons, Columbia University New York New York"},{"name":"Department of Neuroinformatics, Donders Centre for Neuroscience Radboud University 6525 Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misha","family":"Tsodyks","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Weizmann Institute of Science Rehovot 76100 Israel"},{"name":"Department of Neuroscience, Center for Theoretical Neuroscience College of Physicians and Surgeons, Columbia University New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00337259"},{"key":"e_1_2_6_3_1","article-title":"A computational model for preplay in the hippocampus","volume":"7","author":"Azizi AH","year":"2013","journal-title":"Front Comp Neurosci"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.58.7738"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.9.3844"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(89)90423-5"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)91483-6"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00586-X"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3698"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)00135-5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.07.027"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1961"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09633"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1306031110"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hipo.20707","article-title":"Disruption of ripple\u2010associated hippocampal activity during rest impairs spatial learning in the rat","volume":"20","author":"Ego\u2010Stengel V","year":"2009","journal-title":"Hippocampus"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20345"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04587"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099901"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.98.148101"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2384"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.01.034"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03721"},{"key":"e_1_2_6_23_1","volume-title":"Methods in neuronal modeling: from synapse to networks","author":"Hansel D","year":"1998"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature00808"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08499"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2106"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3773-10.2011"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1217230"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2012.0532"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.3.2-3.279"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3761-07.2007"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2344"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02078"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)01096-6"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0708711105"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114037"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020110223441"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237147"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016055"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.07-07-01951.1987"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20939"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(76)90055-8"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(71)90358-1"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.450030307"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.10.037"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12112"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1162\/NECO_a_00087"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000869"},{"key":"e_1_2_6_49_1","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1523\/JNEUROSCI.19-04-01236.1999","article-title":"Hippocampal long\u2010term potentiation preserves the fidelity of postsynaptic responses to presynaptic bursts","volume":"19","author":"Selig DK","year":"1999","journal-title":"J Neurosci"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.23.13339"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1063(1996)6:2<149::AID-HIPO6>3.0.CO;2-K"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003648"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1162\/neco.2008.07-06-292"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.2.719"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1063(1996)6:3<271::AID-HIPO5>3.0.CO;2-Q"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1162\/089976698300017502"},{"key":"e_1_2_6_57_1","doi-asserted-by":"crossref","first-page":"RC50","DOI":"10.1523\/JNEUROSCI.20-01-j0003.2000","article-title":"Synchrony generation in recurrent networks with frequency\u2010dependent synapses","volume":"20","author":"Tsodyks M","year":"2000","journal-title":"J Neurosci"},{"key":"e_1_2_6_58_1","first-page":"81","article-title":"Associative memory and hippocampal place cells","volume":"6","author":"Tsodyks M","year":"1995","journal-title":"Int J Neural Syst"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1829"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(69)90092-3"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1997.78.1.393"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8036517"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1235338"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10827-009-0172-4"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1369"}],"container-title":["Hippocampus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhipo.22355","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.22355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hipo.22355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.22355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T21:38:12Z","timestamp":1717277892000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hipo.22355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,25]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1002\/hipo.22355"],"URL":"https:\/\/doi.org\/10.1002\/hipo.22355","archive":["Portico"],"relation":{},"ISSN":["1050-9631","1098-1063"],"issn-type":[{"value":"1050-9631","type":"print"},{"value":"1098-1063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,25]]}}}