{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:05:41Z","timestamp":1790211941252,"version":"4.1.0"},"reference-count":104,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T00:00:00Z","timestamp":1544486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01\u2010MH106512 R01\u2010MH111790"],"award-info":[{"award-number":["R01\u2010MH106512 R01\u2010MH111790"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["T32\u2010NS047987"],"award-info":[{"award-number":["T32\u2010NS047987"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hippocampus"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Episodic memory is thought to rely on interactions of the hippocampus with other regions of the distributed hippocampal\u2010cortical network (HCN) via interregional activity synchrony in the theta frequency band. We sought to causally test this hypothesis using network\u2010targeted transcranial magnetic stimulation. Healthy human participants completed four experimental sessions, each involving a different stimulation pattern delivered to the same individualized parietal cortex location of the HCN for all sessions. There were three active stimulation conditions, including continuous theta\u2010burst stimulation, intermittent theta\u2010burst stimulation, and beta\u2010frequency (20\u2010Hz) repetitive stimulation, and one sham condition. Resting\u2010state fMRI and episodic memory testing were used to assess the impact of stimulation on hippocampal fMRI connectivity related to retrieval success. We hypothesized that theta\u2010burst stimulation conditions would most strongly influence hippocampal\u2010HCN fMRI connectivity and retrieval, given the hypothesized relevance of theta\u2010band activity for HCN memory function. Continuous theta\u2010burst stimulation improved item retrieval success relative to sham and relative to beta\u2010frequency stimulation, whereas intermittent theta\u2010burst stimulation led to numerical but nonsignificant item retrieval improvement. Mean hippocampal fMRI connectivity did not vary for any stimulation conditions, whereas individual differences in retrieval improvements due to continuous theta\u2010burst stimulation were associated with corresponding increases in fMRI connectivity between the hippocampus and other HCN locations. No such memory\u2010related connectivity effects were identified for the other stimulation conditions, indicating that only continuous theta\u2010burst stimulation affected memory\u2010related hippocampal\u2010HCN connectivity. Furthermore, these effects were specific to the targeted HCN, with no significant memory\u2010related fMRI connectivity effects for two distinct control brain networks. These findings support a causal role for fMRI connectivity of the hippocampus with the HCN in episodic memory retrieval and indicate that contributions of this network to retrieval are particularly sensitive to continuous theta\u2010burst noninvasive stimulation.<\/jats:p>","DOI":"10.1002\/hipo.23054","type":"journal-article","created":{"date-parts":[[2018,11,17]],"date-time":"2018-11-17T10:14:25Z","timestamp":1542449665000},"page":"595-609","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Frequency\u2010specific noninvasive modulation of memory retrieval and its relationship with hippocampal network connectivity"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7234-4695","authenticated-orcid":false,"given":"Molly S.","family":"Hermiller","sequence":"first","affiliation":[{"name":"Northwestern University Interdepartmental Neuroscience Program Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"VanHaerents","sequence":"additional","affiliation":[{"name":"Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommi","family":"Raij","sequence":"additional","affiliation":[{"name":"Northwestern University Interdepartmental Neuroscience Program Northwestern University  Chicago Illinois"},{"name":"Center for Brain Stimulation, Shirley Ryan AbilityLab  Chicago Illinois"},{"name":"Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine Northwestern University  Chicago Illinois"},{"name":"Department of Neurobiology, Weinberg College of Arts and Sciences Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4180-9335","authenticated-orcid":false,"given":"Joel L.","family":"Voss","sequence":"additional","affiliation":[{"name":"Northwestern University Interdepartmental Neuroscience Program Northwestern University  Chicago Illinois"},{"name":"Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine Northwestern University  Chicago Illinois"},{"name":"Department of Medical Social Sciences, Feinberg School of Medicine Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X99002034"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhp223"},{"issue":"7","key":"e_1_2_6_4_1","first-page":"310","article-title":"The hippocampus: Hub of brain network communication for memory","volume":"15","author":"Battaglia F. P.","year":"2011","journal-title":"Trends in Cognitive Sciences"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4163-07.2007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3081-12.2013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1440.011"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2654-13.2014"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00586-X"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.01.037"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4401-12.2013"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00950.2002"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00850.2014"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1006\/cbmr.1996.0014"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2011.06.024"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23803"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.30.051606.094328"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1113103109"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0513-13.2013"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.12.019"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.03.018"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.03.035"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2013.00124"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101430"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308627101"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.01.054"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1776-14.2014"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.10.002"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/09658211.2014.988162"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22621"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2009.10.005"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.12.033"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.08.016"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.03.009"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2016.04.001"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aar2768"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22801"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.20796"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)90579-2"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1620988114"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_01133"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20937"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2017.00170"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.6.1156"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00097"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.10.012"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.05.032"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280502"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90066-X"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv095"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902250105"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.09.036"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.12.042"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2018.07.035"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0b013e318205135f"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2008.09.006"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199807000-00005"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.4.847"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24137"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2013.03.005"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.10.014"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00209.2013"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20141"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3338"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1504196112"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_00533"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1080\/17588928.2018.1521386"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2016.09.001"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2009.08.016"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.02.001"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2012.11.005"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08860"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1089\/brain.2012.0080"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2016.02.006"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_01100"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.20.1.11"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911184107"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1178"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2009.02.028"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1896849"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03207704"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1987-13.2013"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2015.10.004"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20597"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_01300"},{"key":"e_1_2_6_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-007-0991-3"},{"key":"e_1_2_6_87_1","doi-asserted-by":"crossref","unstructured":"ThielscherA AntunesA SaturninoGB.2015Field modeling for transcranial magnetic stimulation: A useful tool to understand the physiological effects of TMS? Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2015:222\u2013225.","DOI":"10.1109\/EMBC.2015.7318340"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10548-009-0115-4"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2011.00170"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.05.049"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.29515"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2149"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.04.017"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.00736"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812097106"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00048.2006"},{"key":"e_1_2_6_97_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4281-13.2014"},{"key":"e_1_2_6_98_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0349-18.2018"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252900"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(82)90099-9"},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3315"},{"key":"e_1_2_6_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.08.075"},{"key":"e_1_2_6_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2015.03.004"},{"key":"e_1_2_6_104_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068910"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00338.2011"}],"container-title":["Hippocampus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhipo.23054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.23054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hipo.23054","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.23054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T17:00:48Z","timestamp":1694365248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hipo.23054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,11]]},"references-count":104,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1002\/hipo.23054"],"URL":"https:\/\/doi.org\/10.1002\/hipo.23054","archive":["Portico"],"relation":{},"ISSN":["1050-9631","1098-1063"],"issn-type":[{"value":"1050-9631","type":"print"},{"value":"1098-1063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,11]]},"assertion":[{"value":"2018-10-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}