{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:17:42Z","timestamp":1783574262852,"version":"3.55.0"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AG076198"],"award-info":[{"award-number":["R01 AG076198"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006976","name":"Lilly Endowment","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006976","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hippocampus"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Path integration is navigation in the absence of environmental landmarks and is a primary cognitive mechanism underlying spatial memory. Path integration performance is primarily assessed in humans using the Triangle Completion Task (TCT). In humans, TCT has shown promise for the early diagnosis of Alzheimer's disease. In rodents, however, path integration is assessed using a wide variety of tasks, but none of which currently provide a homologue for the TCT. As rodents are routinely used as preclinical models, homologous path integration tasks that result in comparable performance metrics between species are important. In the present study, we developed and tested a novel rodent version of the triangle completion task to enhance cross\u2010species comparability of path integration performance. Rats were able to comprehend and perform the task. A group of Alzheimer's disease model rats (TgF344\u2010AD) exhibited similar path integration performance to their wild\u2010type littermates. This work establishes a novel rodent homologue of the triangle completion task, facilitating enhanced reverse translational study of human path integration.<\/jats:p>","DOI":"10.1002\/hipo.70090","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T03:00:37Z","timestamp":1774926037000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>rTCT<\/scp>\n                    : Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1506-0933","authenticated-orcid":false,"given":"Stephen","family":"Duncan","sequence":"first","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3797-1480","authenticated-orcid":false,"given":"Sulaiman","family":"Rehman","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6677-723X","authenticated-orcid":false,"given":"Vladislava","family":"Segen","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)  Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Om","family":"Kalani","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette","family":"Gold","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7047-7965","authenticated-orcid":false,"given":"Lillian","family":"Goldman","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Ramlo","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylene","family":"Stickel","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0694-0998","authenticated-orcid":false,"given":"Dylan","family":"Layfield","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2943-8949","authenticated-orcid":false,"given":"Thomas","family":"Wolbers","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)  Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5581-9636","authenticated-orcid":false,"given":"Zoran","family":"Tiganj","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7006-4112","authenticated-orcid":false,"given":"Ehren L.","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Brain Sciences Indiana University  Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03194870"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.113.1.19"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2022.12.015"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0077579"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/ANBE.1996.0464"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201034368\u2010w"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201018415\u20101"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2901\u201004.2005"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201023801\u2010w"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3672\u201012.2013"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166\u20104328(99)00094\u20107"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.10173"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcac072"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010017\u20100039\u20103"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00345583"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0274\u201023.2023"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22011"},{"key":"e_1_2_9_19_1","first-page":"1491","volume-title":"Brain","author":"Howett D.","year":"2019"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.12.003"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010017\u20101368\u20104"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2020.06.023"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aac8128"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2013.03.019"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.88648.1"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-99872-0_16"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1037\/0096\u20103445.122.1.73"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JNEUMETH.2021.109336"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.08.001"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306\u20104522(98)00448\u20105"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166\u20104328(95)00240\u20105"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2016.03.052"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/297681a0"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035\u2010022\u201000300\u20106"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.14.5287"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201042642\u20103"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14366"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22253"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.13733"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010002\u20101184\u20108"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010004\u20101960\u20108"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.NEUROBIOLAGING.2017.09.024"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.BBR.2021.113661"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010018\u20101678\u20101"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010180432"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/78970"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00601"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735\u20107044.110.1.74"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.NLM.2009.09.009"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adw6404"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2021.11.001"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1006\/anbe.1997.0662"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00209622"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201015805\u20109"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.01.005"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/gbb.12712"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs033"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460\u20109568.2003.02772.x"},{"key":"e_1_2_9_59_1","doi-asserted-by":"crossref","unstructured":"Whishaw I. Q. andB.Gorny.1999.\u201cPath Integration Absent in Scent\u2010Tracking Fimbria\u2010Fornix Rats: Evidence for Hippocampal Involvement in \u2018Sense of Direction\u2019 and \u2018Sense of Distance\u2019 Using Self\u2010Movement Cues.\u201d","DOI":"10.1523\/JNEUROSCI.19-11-04662.1999"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010010\u20102460\u20107"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201028551\u2010x"}],"container-title":["Hippocampus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.70090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hipo.70090","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hipo.70090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T09:07:44Z","timestamp":1779786464000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hipo.70090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,30]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/hipo.70090"],"URL":"https:\/\/doi.org\/10.1002\/hipo.70090","archive":["Portico"],"relation":{},"ISSN":["1050-9631","1098-1063"],"issn-type":[{"value":"1050-9631","type":"print"},{"value":"1098-1063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,30]]},"assertion":[{"value":"2025-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70090"}}