{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T13:00:04Z","timestamp":1789390804849,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T00:00:00Z","timestamp":1444089600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T00:00:00Z","timestamp":1444089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1002\/hon.2264","type":"journal-article","created":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T08:07:13Z","timestamp":1444118833000},"page":"335-340","source":"Crossref","is-referenced-by-count":2,"title":["Oxidative status in treatment-na\u00efve essential thrombocythemia: a pilot study in a single center"],"prefix":"10.1002","volume":"35","author":[{"given":"Alessandra","family":"Iurlo","sequence":"first","affiliation":[{"name":"Oncohematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"},{"name":"Oncohematology Unit of the Elderly; IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachele","family":"De Giuseppe","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology and BMT Unit, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation, Department of Biomedical, Surgical, and Dental Sciences; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariarita","family":"Scium\u00e8","sequence":"additional","affiliation":[{"name":"Oncohematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Cattaneo","sequence":"additional","affiliation":[{"name":"Oncohematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Fermo","sequence":"additional","affiliation":[{"name":"Oncohematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"De Vita","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology and BMT Unit, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation, Department of Biomedical, Surgical, and Dental Sciences; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Consonni","sequence":"additional","affiliation":[{"name":"Epidemiology Unit, Department of Preventive Medicine; IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Maiavacca","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Chemistry and Microbiology; IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizia","family":"Bamonti","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology and BMT Unit, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation, Department of Biomedical, Surgical, and Dental Sciences; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Gianelli","sequence":"additional","affiliation":[{"name":"Hematopathology Service, Division of Pathology, Department of Pathophysiology and Transplantation, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agostino","family":"Cortelezzi","sequence":"additional","affiliation":[{"name":"Oncohematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation; University of Milan; Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,6]]},"reference":[{"key":"10.1002\/hon.2264-BIB0001|hon2264-cit-0001","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/07315724.2011.10719943","article-title":"Effects of encapsulated fruit and vegetable juice powder concentrates on oxidative status in heavy smokers","volume":"30","author":"Novembrino","year":"2011","journal-title":"J Am Coll Nutr"},{"key":"10.1002\/hon.2264-BIB0002|hon2264-cit-0002","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.lfs.2012.03.002","article-title":"Intracellular glutathione protects human monocyte-derived macrophages from hypochlorite damage","volume":"90","author":"Yang","year":"2012","journal-title":"Life Sci"},{"key":"10.1002\/hon.2264-BIB0003|hon2264-cit-0003","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0891-5849(98)00213-5","article-title":"Changes in glutathione status and the antioxidant system in blood and in cancer cells associate with tumour growth in vivo","volume":"26","author":"Navarro","year":"1999","journal-title":"Free Radic Biol Med"},{"key":"10.1002\/hon.2264-BIB0004|hon2264-cit-0004","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s12291-008-0072-9","article-title":"Oxidative stress and antioxidant status in patients with chronic myeloid leukemia","volume":"23","author":"Ahmad","year":"2008","journal-title":"Indian J Clin Biochem"},{"key":"10.1002\/hon.2264-BIB0005|hon2264-cit-0005","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.exphem.2010.07.005","article-title":"Oxidative stress is increased in primary and post-polycythemia vera myelofibrosis","volume":"38","author":"Vener","year":"2010","journal-title":"Exp Hematol"},{"key":"10.1002\/hon.2264-BIB0006|hon2264-cit-0006","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.clinbiochem.2012.07.100","article-title":"Changes in advanced oxidation protein products, advanced glycation end products, and s-nitrosylated proteins, in patients affected by polycythemia vera and essential thrombocythemia","volume":"45","author":"Musolino","year":"2012","journal-title":"Clin Biochem"},{"key":"10.1002\/hon.2264-BIB0007|hon2264-cit-0007","first-page":"2860","article-title":"Increased oxidative stress in patients with essential thrombocythemia","volume":"17","author":"Durmus","year":"2013","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1002\/hon.2264-BIB0008|hon2264-cit-0008","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1038\/leu.2013.102","article-title":"A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression","volume":"27","author":"Marty","year":"2013","journal-title":"Leukemia"},{"key":"10.1002\/hon.2264-BIB0009|hon2264-cit-0009","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1182\/blood-2011-11-394775","article-title":"Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?","volume":"119","author":"Hasselbalch","year":"2012","journal-title":"Blood"},{"key":"10.1002\/hon.2264-BIB0010|hon2264-cit-0010","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1586\/17474086.2013.876356","article-title":"Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms","volume":"7","author":"Hasselbalch","year":"2014","journal-title":"Expert Rev Hematol"},{"key":"10.1002\/hon.2264-BIB0011|hon2264-cit-0011","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1038\/ki.2008.516","article-title":"Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease","volume":"111","author":"Cachofeiro","year":"2008","journal-title":"Kidney Int Suppl"},{"key":"10.1002\/hon.2264-BIB0012|hon2264-cit-0012","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(05)74230-6","article-title":"Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders","volume":"365","author":"Baxter","year":"2005","journal-title":"Lancet"},{"key":"10.1002\/hon.2264-BIB0013|hon2264-cit-0013","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1056\/NEJMoa1311347","article-title":"Somatic mutations of calreticulin in myeloproliferative neoplasms","volume":"369","author":"Klampfl","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1002\/hon.2264-BIB0014|hon2264-cit-0014","first-page":"48","volume-title":"WHO Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues","year":"2008"},{"key":"10.1002\/hon.2264-BIB0015|hon2264-cit-0015","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1097\/01.TP.0000090344.61975.F0","article-title":"Oxidative stress in kidney transplant patients","volume":"76","author":"Campise","year":"2003","journal-title":"Transplantation"},{"key":"10.1002\/hon.2264-BIB0016|hon2264-cit-0016","doi-asserted-by":"crossref","first-page":"281510","DOI":"10.1155\/2014\/281510","article-title":"Improvement of oxidative and metabolic parameters by cellfood administration in patients affected by neurodegenerative diseases on chelation treatment","volume":"2014","author":"Fulgenzi","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1002\/hon.2264-BIB0017|hon2264-cit-0017","doi-asserted-by":"crossref","first-page":"93","DOI":"10.5607\/en.2014.23.1.93","article-title":"Glutathione protects brain endothelial cells from hydrogen peroxide-induced oxidative stress by increasing nrf2 expression","volume":"23","author":"Song","year":"2014","journal-title":"Exp Neurobiol"},{"key":"10.1002\/hon.2264-BIB0018|hon2264-cit-0018","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.3324\/haematol.2012.082560","article-title":"Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation","volume":"98","author":"Hurtado-Nedelec","year":"2013","journal-title":"Haematologica"},{"key":"10.1002\/hon.2264-BIB0019|hon2264-cit-0019","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1538-7836.2004.01085.x","article-title":"Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes","volume":"3","author":"Madamanchi","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1002\/hon.2264-BIB0020|hon2264-cit-0020","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/sj.leu.2404955","article-title":"Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms","volume":"22","author":"Tefferi","year":"2008","journal-title":"Leukemia"},{"key":"10.1002\/hon.2264-BIB0021|hon2264-cit-0021","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/ajh.23895","article-title":"Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification, and management","volume":"90","author":"Tefferi","year":"2015","journal-title":"Am J Hematol"},{"key":"10.1002\/hon.2264-BIB0022|hon2264-cit-0022","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/ejh.12389","article-title":"Mutations and thrombosis in essential thrombocythemia: prognostic interaction with age and thrombosis history","volume":"94","author":"Gangat","year":"2015","journal-title":"Eur J Haematol"},{"key":"10.1002\/hon.2264-BIB0023|hon2264-cit-0023","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1182\/blood-2012-07-444067","article-title":"Development and validation of an international prognostic score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis)","volume":"120","author":"Barbui","year":"2012","journal-title":"Blood"},{"key":"10.1002\/hon.2264-BIB0024|hon2264-cit-0024","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/nature05487","article-title":"Mechanisms linking obesity with cardiovascular disease","volume":"444","author":"Van Gaal","year":"2006","journal-title":"Nature"},{"key":"10.1002\/hon.2264-BIB0025|hon2264-cit-0025","first-page":"211","article-title":"The glutathione system. II. Other enzymes, thiol-disulfide metabolism, inflammation, and immunity, functions","volume":"3","author":"Kulinsky","year":"2009","journal-title":"Biochemistry"},{"key":"10.1002\/hon.2264-BIB0026|hon2264-cit-0026","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2174\/187152906779010719","article-title":"Vascular C-reactive protein in the pathogenesis of coronary artery disease: role of vascular inflammation and oxidative stress","volume":"6","author":"Inoue","year":"2006","journal-title":"Cardiovasc Hematol Disord Drug Targets"},{"key":"10.1002\/hon.2264-BIB0027|hon2264-cit-0027","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036325","article-title":"Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells","volume":"7","author":"Raza","year":"2012","journal-title":"PLoS One"},{"key":"10.1002\/hon.2264-BIB0028|hon2264-cit-0028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0103379","article-title":"NAC attenuates LPS-induced toxicity in aspirin-sensitized mouse macrophages via suppression of oxidative stress and mitochondrial dysfunction","volume":"9","author":"Raza","year":"2014","journal-title":"PLoS One"}],"container-title":["Hematological Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhon.2264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhon.2264","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/hon.2264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T19:44:45Z","timestamp":1625168685000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hon.2264"}},"subtitle":["Oxidative status in essential thrombocythemia"],"short-title":[],"issued":{"date-parts":[[2015,10,6]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"URL":"https:\/\/doi.org\/10.1002\/hon.2264","archive":["Portico"],"relation":{},"ISSN":["0278-0232"],"issn-type":[{"value":"0278-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10,6]]}}}