{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T17:40:33Z","timestamp":1777052433905,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Epidemiologic studies of non\u2010Hodgkin lymphoma (NHL) in Eastern Europe are scarce in the literature. We report the experience of the \u201cIon Chiricuta\u201d Institute of Oncology in Cluj\u2010Napoca (IOCN), Romania, in the diagnosis and outcome of patients with NHL. We studied 184 consecutive NHL patients diagnosed in the Pathology Department of IOCN during the years 2004\u20132006. We also obtained epidemiological data from the Northwestern (NW) Cancer Registry. In the IOCN series, the most common lymphoma subtype was diffuse large B\u2010cell lymphoma (43.5%), followed by the chronic lymphocytic leukaemia\/small lymphocytic lymphoma (21.2%). T\u2010cell lymphomas represented a small proportion (8.2%). The median age of the patients was 57\u2009years, with a male\u2010to\u2010female ratio of 0.94. Patients with indolent B\u2010cell lymphomas had the best overall survival, whereas those with mantle cell lymphoma had the worst survival. The NW Cancer Registry data showed that the occurrence of NHL in the NW region of Romania was higher in men [world age\u2010standardized incidence rate\/100\u2009000 (ASR)\u20145.9; 95% CI 5.1\u20136.6] than in women (ASR\u20144.1; 95% CI 3.5\u20134.7) with age\u2010standardized male\u2010to\u2010female ratio of 1.44 (<jats:italic>p<\/jats:italic>\u2009=\u20090.038). Chronic lymphocytic leukaemia\/small lymphocytic lymphoma was the most common NHL in the NW region of Romania, accounting for 43% of all cases, followed by diffuse large B\u2010cell lymphoma (36%). The 5\u2010year, age\u2010standardized cumulative relative survival for NHL in the County of Cluj in NW Romania, for the period of 2006\u20132010, was 51.4%, with 58.4% survival for men and 43.2% for women. Additional studies of NHL in Eastern Europe are needed. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hon.2266","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T13:31:28Z","timestamp":1445347888000},"page":"198-205","source":"Crossref","is-referenced-by-count":5,"title":["Non\u2010Hodgkin lymphoma in Romania: a single\u2010centre experience"],"prefix":"10.1002","volume":"35","author":[{"given":"Bogdan","family":"Fetica","sequence":"first","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patriciu","family":"Achimas\u2010Cadariu","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"},{"name":"University of Medicine and Pharmacy \u201cIuliu Hatieganu\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogdan","family":"Pop","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cIuliu Hatieganu\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delia","family":"Dima","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljubomir","family":"Petrov","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"},{"name":"University of Medicine and Pharmacy \u201cIuliu Hatieganu\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anamarija M.","family":"Perry","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Manitoba  Winnipeg Manitoba Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharat N.","family":"Nathwani","sequence":"additional","affiliation":[{"name":"Department of Pathology City of Hope National Medical Center  Duarte CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans K.","family":"M\u00fcller\u2010Hermelink","sequence":"additional","affiliation":[{"name":"Institute of Pathology University of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Diebold","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology and Cytology Hotel\u2010Dieu, University Denis Diderot  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth A.","family":"MacLennan","sequence":"additional","affiliation":[{"name":"Section of Pathology and Leeds Institute of Molecular Medicine St. James University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamaria","family":"Fulop","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaiela L.","family":"Blaga","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Coza","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian Al.","family":"Nicula","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Irimie","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Ion Chiricuta\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"},{"name":"University of Medicine and Pharmacy \u201cIuliu Hatieganu\u201d Cluj\u2010Napoca  Cluj\u2010Napoca Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis D.","family":"Weisenburger","sequence":"additional","affiliation":[{"name":"Department of Pathology City of Hope National Medical Center  Duarte CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,20]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow SH","year":"2008"},{"key":"e_1_2_9_3_1","unstructured":"WeisenburgerD.Malignant lymphomas around the world with special regard on lymphomas in South\u2010East Europe. 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