{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:14:39Z","timestamp":1791486879728,"version":"4.3.4"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Thai Society of Hematology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Systemic reports on the descriptive epidemiology of non\u2010Hodgkin lymphoma (NHL) from Southeast Asia are scarce. A nationwide multi\u2010institutional registry was conducted to compare the histopathology, clinical features, and survival of Thai adult patients with NHL using large registries, especially those from Far East Asia (FEA). Using a web\u2010based registry system, 13 major medical centers from the 4 geographic regions of Thailand prospectively collected, from 2007 to 2014, the diagnostic pathology, according to the World Health Organization classification, 2008, clinical features and survival of 4056 patients who were newly diagnosed with NHL. The median age of the patients was 56\u00a0years (range, 16\u201099\u00a0years). The male\u2010to\u2010female ratio was 1.3:1. From the total of 4056 patients, T\/NK\u2010cell lymphoma (TNKCL) accounted for 12.6% of cases, and 5.1% had human immunodeficiency virus\u2013associated lymphoma. The four leading histological subtypes were diffuse large B\u2010cell lymphoma, not otherwise specified (58.1%); follicular lymphoma (5.6%); extranodal mucosa\u2010associated lymphoid tissue lymphoma (5.2%); and peripheral T\u2010cell lymphoma, not otherwise specified (4.0%). With a median follow\u2010up duration of 46.1\u00a0months, the median overall survival of B\u2010cell NHL was significantly longer than that of patients with TNKCL (76.5 vs 28.8\u00a0months, <jats:italic>P\u00a0=<\/jats:italic>\u00a0.0001). Compared to FEA, the Thai registry had an approximately one\u2010half lower relative frequency of TNKCL; the prevalence of extranodal mucosa\u2010associated lymphoid tissue lymphoma was much lower than in Korea, and the frequency of extranodal TNKCL, nasal type, was strikingly low compared to China. It is concluded that while the median age of Thai patients with NHL was approximately a decade younger than for Caucasians, the long\u2010term survival rates for most histological subtypes were comparable. While the histological distribution generally complied with the characteristic Asian features, some differences from FEA were observed.<\/jats:p>","DOI":"10.1002\/hon.2392","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T06:23:56Z","timestamp":1490336636000},"page":"28-36","source":"Crossref","is-referenced-by-count":41,"title":["Non\u2010Hodgkin lymphoma in South East Asia: An analysis of the histopathology, clinical features, and survival from Thailand"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2687-3611","authenticated-orcid":false,"given":"Tanin","family":"Intragumtornchai","sequence":"first","affiliation":[{"name":"Division of Hematology, Department of Medicine, Faculty of Medicine Chulalongkorn Universit  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udomsak","family":"Bunworasate","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department 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