{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:00:37Z","timestamp":1770015637815,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,4]],"date-time":"2017-06-04T00:00:00Z","timestamp":1496534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary effusion lymphoma is a rare non\u2010Hodgkin lymphoma that presents with pleural effusions and lacking of tumour mass. It is universally associated with human herpesvirus 8 (HHV8) and is more frequent among immunosuppressed patients. There is no standard treatment, chemotherapy and anti\u2010HIV therapy have been used with poor results, but there is still no strong evidence supporting the use of valganciclovir. We present the case of a HIV positive man that presented with pleural effusion compatible with primary effusion lymphoma and positivity for HHV8 DNA in blood. Bortezomib\u2010containing treatment protocol was started, but the disease progressed within the chemotherapy. Therefore, treatment with oral valganciclovir was decided and the patient achieved a sustained radiological complete response. HHV8 DNA turned negative 6\u00a0months after starting the treatment with valganciclovir.<\/jats:p>","DOI":"10.1002\/hon.2445","type":"journal-article","created":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T03:46:40Z","timestamp":1496634400000},"page":"316-319","source":"Crossref","is-referenced-by-count":9,"title":["Case report of a primary effusion lymphoma successfully treated with oral valganciclovir after failing chemotherapy"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8484-1442","authenticated-orcid":false,"given":"Juan","family":"Marquet","sequence":"first","affiliation":[{"name":"Hematology Hospital Universitario Ramon y Cajal  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyra","family":"Velazquez\u2010Kennedy","sequence":"additional","affiliation":[{"name":"Hematology Hospital Universitario Ramon y Cajal  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Hematology Hospital Universitario Ramon y Cajal  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amparo","family":"Benito","sequence":"additional","affiliation":[{"name":"Pathology Hospital Universitario Ramon y Cajal  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda\u2010Jes\u00fas","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Ram\u00f3n y Cajal de Madrid Hospital Universitario  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Antonio","family":"Garcia\u2010Vela","sequence":"additional","affiliation":[{"name":"Hematology Hospital Universitario de Getafe  Madrid 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