{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:10:29Z","timestamp":1772118629115,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T00:00:00Z","timestamp":1566691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In absence of red blood cells disease or immune defect, parvovirus B19 (PVB\u201019) is usually considered as a benign condition. Here, we report the case of a 10\u2010year\u2010old boy, previously healthy, presenting with a PVB\u201019 infection revealed by a bicytopenia and a voluminous axillary adenopathy. Pathophysiology examination showed reactional lymphoid population. Nine months later and in the absence of remission, a new biopsy of the same adenopathy revealed a Hodgkin lymphoma with area of T\u2010cell rich aggressive large B\u2010cell lymphoma. This case suggests PVB\u201019 as potential trigger of this malignant childhood hemopathy. Although no definitive conclusion can be drawn, our clinical case questions the role of PVB\u201019 in lymphomagenesis.<\/jats:p>","DOI":"10.1002\/hon.2665","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T14:03:58Z","timestamp":1565705038000},"page":"483-486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aggressive large B\u2010cell lymphoma triggered by a parvovirus B19 infection in a previously healthy child"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2908-5768","authenticated-orcid":false,"given":"Laura","family":"Olivier\u2010Gougenheim","sequence":"first","affiliation":[{"name":"Institute of Pediatric Hematology and Oncology Hospices Civils de Lyon, Claude Bernard Lyon I University Lyon 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