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The morphology of the large cells, the type of infiltration of the lymph node simulating metastatic carcinoma or malignant histiocytosis were highly suggestive of a new type of high grade malignancy lymphoma recently described which is called \u2018large cell anaplastic ML\u2019. The immunolabelling study confirmed this diagnosis, demonstrating the following phenotype CD4, CD25 (TAC), CD30 (Ki\u20101), OKT 9 (transferrin receptor), EMA and HLA DR positivity. The tumour cells were negative for the other T, B and histiomono\u2010cytic markers. This case, of a large cell anaplastic Ki\u20101 positive lymphoma, expressing CD4, in a renal graft recipient shows that high grade ML in such patients are not all of the B cell type.<\/jats:p>","DOI":"10.1002\/hon.2900070607","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T20:04:47Z","timestamp":1171915487000},"page":"441-449","source":"Crossref","is-referenced-by-count":21,"title":["Primary intestinal lymphoma of Ki\u20101 large cell anaplastic type with mesenteric lymph node and spleen involvement in a renal transplant recipient"],"prefix":"10.1002","volume":"7","author":[{"given":"J.","family":"Audouin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Le Tourneau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Diebold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Reynes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Tabbah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bernadou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(86)80046-6"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198506000-00021"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-54-641-418"},{"key":"e_1_2_1_5_1","first-page":"4262","article-title":"Polymorphic diffuse B cell hyperplasias and lymphomas in renal transplant recipients","volume":"41","author":"Frizzera G.","year":"1981","journal-title":"Cancer Res."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198801000-00008"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.39.9.993"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198204153061506"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1182\/blood.V68.5.1042.1042","article-title":"Childhood Ki\u20101 lymphoma presenting with skin lesions and peripheral lymphadenopathy","volume":"68","author":"Kadin M. 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