{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T15:31:19Z","timestamp":1771515079774,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T00:00:00Z","timestamp":1172793600000},"content-version":"vor","delay-in-days":5631,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[1991,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Legionella pneumonia is an increasingly frequently reported complication in immunocompromised patients, particularly patients with hairy cell leukemia (HCL) in active phase. The most important predisposing factor seems to be the quantitative and qualitative defect of the monocytic\u2010macrophagic system characteristic of HCL. We report a case of severe <jats:italic>Legionella pneumophila<\/jats:italic> infection with multisystem involvement in a patient with HCL in stable partial remission obtained after therapy with interferon. In our patient recovery of a normal monocyte count did not protect against a legionella infection, indicating that this pathogen should always be sought in HCL patients even those in clinical and hematologic remission. Early diagnosis and appropriate treatment may reduce the mortality of this serious complication.<\/jats:p>","DOI":"10.1002\/hon.2900090302","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T19:02:30Z","timestamp":1171911750000},"page":"125-128","source":"Crossref","is-referenced-by-count":10,"title":["Severe <i>legionella pneumophila<\/i> infection in a patient with hairy cell leukemia in partial remission after <i>a<\/i> interferon treatment"],"prefix":"10.1002","volume":"9","author":[{"given":"Franca","family":"Radaelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Langer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ornella","family":"Chiorboli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Proietti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Baldini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,6]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"2323","article-title":"Leuc\u00e9mie \u00e0 tricholeucocytes r\u00e9v\u00e9l\u00e9e lors d'une pnuemonie \u00e0 Legionella pneumophila","volume":"13","author":"Bergmann J. F.","year":"1984","journal-title":"La Press Med."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.144.12.2373"},{"key":"e_1_2_1_4_1","unstructured":"Dournon E. Rajagopalan P. Vilde' J. L. Pocidalo J. J.(1985).Quinolones et legionelloses. In: Pocidalo. J. J. Vachon F. Arnette Eds.Les Nouvelles Quinolones. Paris 159\u2013179."},{"key":"e_1_2_1_5_1","first-page":"7","article-title":"Report of a multi\u2010institutional study of 193 patients with hairy cell leukemia treated with interferon\u2010alfa 2b","volume":"15","author":"Golomb H. M.","year":"1988","journal-title":"Sem. Oncol."},{"key":"e_1_2_1_6_1","first-page":"394","article-title":"Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor","volume":"11","author":"Korsmeyer S. J.","year":"1984","journal-title":"Semin. 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