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In our single\u2010center validation in 381 FL patients, lymphopenia was less frequent than in the original publication and thus the distribution of risk categories was different. Although it was not able to properly predict time to first treatment, FLIPI\u2010L performed slightly better than FLIPI alone in the prediction of response, early relapse, progression\u2010free and overall survival, and histological transformation. This new tool or others encompassing parameters from the microenvironment might improve upon the prognostic ability of classical scores.<\/jats:p>","DOI":"10.1002\/hon.2953","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T11:21:25Z","timestamp":1638271285000},"page":"297-301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First external validation of the FLIPI\u2010L score in a single\u2010center series of patients with follicular lymphoma"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-4971","authenticated-orcid":false,"given":"Pablo","family":"Mozas","sequence":"first","affiliation":[{"name":"Department of Haematology Hospital Cl\u00ednic de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Rivero","sequence":"additional","affiliation":[{"name":"Department of Haematology 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