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We found that the outcome of a localized relapse after CARs treated with radiotherapy was comparable to patients without a relapse. With the knowledge from the collected real\u2010world data, we should launch prospective clinical trials to further improve the use of radiotherapy, and overall the efficacy of CAR T\u2010cell therapies for patients with aggressive lymphomas.<\/jats:p>","DOI":"10.1002\/hon.70124","type":"journal-article","created":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T11:48:38Z","timestamp":1756640918000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["CAR T\u2010Cell Therapies for Patients With Relapsed and Refractory Aggressive Lymphomas: Real\u2010World Experiences From a Single Center on the Use of Radiotherapy"],"prefix":"10.1002","volume":"43","author":[{"given":"J.T.","family":"Jutzi","sequence":"first","affiliation":[{"name":"Department of Medical Oncology Inselspital Bern University Hospital University of Bern  Bern 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