{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T08:40:56Z","timestamp":1700037656592},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,5,16]],"date-time":"2007-05-16T00:00:00Z","timestamp":1179273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of an EBV\u2010associated high grade B\u2010cell lymphoproliferative disorder occurring in the synovial membrane of an elderly patient with gout arthropathy. The EBV\u2010infected B\u2010cells displayed a pattern of viral gene expression (EBNA2<jats:sup>+<\/jats:sup>\/LMP1<jats:sup>+<\/jats:sup>) typically seen during primary EBV\u2010infection and in lymphoproliferations occurring in immunosuppressed individuals. This case conforms to senile EBV\u2010associated lymphoproliferative disorders previously reported only in Japanese patients. We suggest that an impaired EBV\u2010specific T\u2010cell immunity, local or systemic, may play a role in the development of this disorder and that chronic diseases such as gout may be contributing factors. Copyright \u00a9 2007 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hon.814","type":"journal-article","created":{"date-parts":[[2007,5,16]],"date-time":"2007-05-16T21:50:02Z","timestamp":1179352202000},"page":"140-142","source":"Crossref","is-referenced-by-count":2,"title":["Senile EBV\u2010associated B\u2010cell lymphoproliferative disorder of prepatellar bursa in an elderly patient with multifocal urate arthropathy"],"prefix":"10.1002","volume":"25","author":[{"given":"Susanna","family":"Mueller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Aigner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Haag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Niedobitek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,5,16]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2613.2001.iep190.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00838047"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1006\/scbi.1996.0026"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000126149.96627.82"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1999.00629.x"},{"key":"e_1_2_1_7_2","first-page":"ECR31","article-title":"EBV\u2010associated synovial lymphoma in a chronically inflamed joint in rheumatoid arthritis receiving prolonged methotrexate treatment","volume":"91","author":"Chim CS","year":"2006","journal-title":"Haematologica"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.11.3909"},{"key":"e_1_2_1_9_2","article-title":"Lymphoproliferative disorders in rheumatoid arthritis: clinicopathological analysis of 76 cases in relation to methotrexate medication","author":"Hoshida Y","year":"2006","journal-title":"J Rheumatol"},{"key":"e_1_2_1_10_2","first-page":"1280","article-title":"High expression of the Epstein\u2010Barr virus latent protein EB nuclear antigen\u20102 on pyothorax\u2010associated lymphomas","volume":"143","author":"Sasajima S","year":"1993","journal-title":"Am J Pathol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(94)90091-4"},{"key":"e_1_2_1_12_2","first-page":"1","article-title":"Epstein\u2010Barr virus in pyothorax\u2010associated pleural lymphoma","volume":"143","author":"Fukayama M","year":"1993","journal-title":"Am J Pathol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9896(199711)183:3<287::AID-PATH932>3.0.CO;2-Q"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2005.11.010"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/ar1908"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200301000-00003"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.46.1"}],"container-title":["Hematological Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhon.814","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hon.814","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T08:11:56Z","timestamp":1700035916000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hon.814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,16]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1002\/hon.814"],"URL":"https:\/\/doi.org\/10.1002\/hon.814","archive":["Portico"],"relation":{},"ISSN":["0278-0232","1099-1069"],"issn-type":[{"value":"0278-0232","type":"print"},{"value":"1099-1069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,16]]}}}