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The current WHO classification recognizes nine distinct clinicopathologic peripheral T\u2010cell NHLs, being the \u2018unspecified variant\u2019 (PTCL\u2010U) the most common subtype. These neoplasms often present in advanced stage at diagnosis, and most commonly have an aggressive clinical course requiring prompt treatment. The rarity of these tumours requires additional studies to better understand their biology and search for new therapies which may hopefully improve the dismal outcome of most patients. This review aims to describe the pathobiological aspects as well the clinical characteristics and current therapeutic strategies of the PTCLs, with special attention to the group of PTCL\u2010U Copyright \u00a9 2007 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hon.836","type":"journal-article","created":{"date-parts":[[2007,11,29]],"date-time":"2007-11-29T13:16:22Z","timestamp":1196342182000},"page":"8-20","source":"Crossref","is-referenced-by-count":51,"title":["Peripheral T\u2010cell lymphomas, unspecified (or not otherwise specified): a review"],"prefix":"10.1002","volume":"26","author":[{"given":"Delvys","family":"Rodriguez\u2010Abreu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volmar Belisario","family":"Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Zucca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,29]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"191","volume-title":"World health organization classification of tumours. 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