{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:12:43Z","timestamp":1768641163971,"version":"3.49.0"},"reference-count":169,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,12,7]],"date-time":"2010-12-07T00:00:00Z","timestamp":1291680000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The telomeric checkpoint is emerging as a critical sensor of cellular damage, playing a major role in human aging and cancer development. In the meantime, telomere biology is rapidly evolving from a basic discipline to a translational branch, capable of providing major hints for biomarker development, risk assessment and targeted treatment of cancer. These advances have a number of implications in the biology of lymphoid tumours. Moreover, there is considerable interest in the potential role of telomeric dysfunction in the wide array of immunological abnormalities, grouped under the definition of \u2018immunosenescence\u2019. This review will summarize the impact of recent advances in telomere biology on the physiology and pathology of the B lymphocyte, with special interest in immunosenescence and lymphomagenesis. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hon.937","type":"journal-article","created":{"date-parts":[[2010,3,8]],"date-time":"2010-03-08T06:34:03Z","timestamp":1268030043000},"page":"157-167","source":"Crossref","is-referenced-by-count":15,"title":["Telomeres and telomerase in normal and malignant B\u2010cells"],"prefix":"10.1002","volume":"28","author":[{"given":"Chiara","family":"Lobetti\u2010Bodoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Bernocco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Genuardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Boccadoro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Ladetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,7]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0531-5565(01)00160-7"},{"key":"e_1_2_11_3_2","first-page":"263","article-title":"Telomerase, checkpoints and cancer","volume":"29","author":"Harley CB","year":"1997","journal-title":"Cancer Surv"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.18.8348"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.21.9857"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2393"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8924(01)82148-6"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri890"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00062752-200101000-00010"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.20.10827"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06639.x"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/345458a0"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(73)90198-7"},{"key":"e_1_2_11_14_2","first-page":"1496","article-title":"Principle of marginotomy in template synthesis of polynucleotides","volume":"201","author":"Olovnikov AM","year":"1971","journal-title":"Dokl Akad Nauk SSSR"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.3.1191"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.24.11091"},{"key":"e_1_2_11_17_2","first-page":"4918","article-title":"Telomere length and telomerase activity predict survival in patients with B cell chronic lymphocytic leukemia","volume":"58","author":"Bechter OE","year":"1998","journal-title":"Cancer Res"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-09-111245"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2007.00817.x"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-12-4412"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1346005"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1205082"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/350569a0"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.53.070184.001115"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/newbio239197a0"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2047"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm893"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06666.x"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901131"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.2500"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5349.349"},{"key":"e_1_2_11_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81123-X"},{"key":"e_1_2_11_33_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.19.10075"},{"key":"e_1_2_11_34_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7544491"},{"key":"e_1_2_11_35_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079161"},{"key":"e_1_2_11_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/78592"},{"key":"e_1_2_11_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.3.472"},{"key":"e_1_2_11_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80580-2"},{"key":"e_1_2_11_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/33345"},{"key":"e_1_2_11_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)80006-4"},{"key":"e_1_2_11_41_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7544492"},{"key":"e_1_2_11_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/62.4.367"},{"key":"e_1_2_11_43_2","doi-asserted-by":"publisher","DOI":"10.1006\/excr.2001.5409"},{"key":"e_1_2_11_44_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.1385"},{"key":"e_1_2_11_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6408(1999)25:4<397::AID-DVG13>3.0.CO;2-J"},{"key":"e_1_2_11_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0888-7543(02)00033-2"},{"key":"e_1_2_11_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(02)02110-2"},{"key":"e_1_2_11_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(61)90192-6"},{"key":"e_1_2_11_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.07.003"},{"key":"e_1_2_11_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2007.02.026"},{"key":"e_1_2_11_51_2","doi-asserted-by":"publisher","DOI":"10.4161\/cc.5.8.2638"},{"key":"e_1_2_11_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8924(03)00170-3"},{"key":"e_1_2_11_53_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra062285"},{"key":"e_1_2_11_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81902-9"},{"key":"e_1_2_11_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(99)00047-7"},{"key":"e_1_2_11_56_2","doi-asserted-by":"publisher","DOI":"10.1038\/88871"},{"key":"e_1_2_11_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.02.003"},{"key":"e_1_2_11_58_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.211053698"},{"key":"e_1_2_11_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(01)00847-3"},{"key":"e_1_2_11_60_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.13.2626"},{"key":"e_1_2_11_61_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.06.018"},{"key":"e_1_2_11_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(02)00702-4"},{"key":"e_1_2_11_63_2","doi-asserted-by":"publisher","DOI":"10.1159\/000167814"},{"key":"e_1_2_11_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1197-1271"},{"key":"e_1_2_11_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb985"},{"key":"e_1_2_11_66_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.182407599"},{"key":"e_1_2_11_67_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.11.2619"},{"key":"e_1_2_11_68_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.37.26141"},{"key":"e_1_2_11_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63180-X"},{"key":"e_1_2_11_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600438"},{"key":"e_1_2_11_71_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.211357798"},{"key":"e_1_2_11_72_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.090013497"},{"key":"e_1_2_11_73_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22120"},{"key":"e_1_2_11_74_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3513"},{"key":"e_1_2_11_75_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23419"},{"key":"e_1_2_11_76_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700710"},{"key":"e_1_2_11_77_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0432"},{"key":"e_1_2_11_78_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.09.160"},{"key":"e_1_2_11_79_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10169"},{"key":"e_1_2_11_80_2","first-page":"2181","article-title":"Prognostic significance of telomeric repeat length alterations in pathological stage I\u2013IIIA non\u2010small cell lung cancer","volume":"20","author":"Hirashima T","year":"2000","journal-title":"Anticancer Res"},{"key":"e_1_2_11_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68239-0"},{"key":"e_1_2_11_82_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1992.tb00081.x"},{"key":"e_1_2_11_83_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003864"},{"key":"e_1_2_11_84_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1062329"},{"key":"e_1_2_11_85_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1998.9674"},{"key":"e_1_2_11_86_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.155.8.3711"},{"key":"e_1_2_11_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2007.11.005"},{"key":"e_1_2_11_88_2","first-page":"169","article-title":"Telomere shortening and ageing of the immune system","volume":"59","author":"Kaszubowska L","year":"2008","journal-title":"J Physiol Pharmacol"},{"key":"e_1_2_11_89_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.6.2471"},{"key":"e_1_2_11_90_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.1.222.222"},{"key":"e_1_2_11_91_2","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0299"},{"key":"e_1_2_11_92_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4141(200007)30:7<1894::AID-IMMU1894>3.0.CO;2-N"},{"key":"e_1_2_11_93_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1997.tb01026.x"},{"key":"e_1_2_11_94_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.3.597"},{"key":"e_1_2_11_95_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.8.4239"},{"key":"e_1_2_11_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80597-X"},{"key":"e_1_2_11_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(03)00018-6"},{"key":"e_1_2_11_98_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.159.3.1068"},{"key":"e_1_2_11_99_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/18.5.1172"},{"key":"e_1_2_11_100_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600598"},{"key":"e_1_2_11_101_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00321-08"},{"key":"e_1_2_11_102_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-005-0557-2"},{"key":"e_1_2_11_103_2","first-page":"207","article-title":"Determination of telomerase activity and telomere length","volume":"113","author":"Wu KD","year":"2005","journal-title":"Methods Mol Med"},{"key":"e_1_2_11_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-9525(92)90232-S"},{"key":"e_1_2_11_105_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.190.2.157"},{"key":"e_1_2_11_106_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03910.x"},{"key":"e_1_2_11_107_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2007.01890.x"},{"key":"e_1_2_11_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66630-5"},{"key":"e_1_2_11_109_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.854299"},{"key":"e_1_2_11_110_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.12.8218"},{"key":"e_1_2_11_111_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-09-178871"},{"key":"e_1_2_11_112_2","first-page":"5917","article-title":"Estrogen activates telomerase","volume":"59","author":"Kyo S","year":"1999","journal-title":"Cancer Res"},{"key":"e_1_2_11_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(99)00748-6"},{"key":"e_1_2_11_114_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603934"},{"key":"e_1_2_11_115_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20226"},{"key":"e_1_2_11_116_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190600687547"},{"key":"e_1_2_11_117_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22372"},{"key":"e_1_2_11_118_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510441103"},{"key":"e_1_2_11_119_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05344.x"},{"key":"e_1_2_11_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2008.03.003"},{"key":"e_1_2_11_121_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-05-092486"},{"key":"e_1_2_11_122_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.7184"},{"key":"e_1_2_11_123_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040857"},{"key":"e_1_2_11_124_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15260-9"},{"key":"e_1_2_11_125_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403537"},{"key":"e_1_2_11_126_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa023143"},{"key":"e_1_2_11_127_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.3.1023"},{"key":"e_1_2_11_128_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200012283432602"},{"key":"e_1_2_11_129_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V94.6.1840"},{"key":"e_1_2_11_130_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V94.6.1848"},{"key":"e_1_2_11_131_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404607"},{"key":"e_1_2_11_132_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1345"},{"key":"e_1_2_11_133_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600763"},{"key":"e_1_2_11_134_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404544"},{"key":"e_1_2_11_135_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-11-4394"},{"key":"e_1_2_11_136_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.399"},{"key":"e_1_2_11_137_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3801015"},{"key":"e_1_2_11_138_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-0099"},{"key":"e_1_2_11_139_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21625"},{"key":"e_1_2_11_140_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn394"},{"key":"e_1_2_11_141_2","first-page":"307","article-title":"Telomere length and hTERT expression in patients with acute myeloid leukemia correlates with chromosomal abnormalities","volume":"90","author":"Hartmann U","year":"2005","journal-title":"Haematologica"},{"key":"e_1_2_11_142_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-11-3451"},{"key":"e_1_2_11_143_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.8.2882"},{"key":"e_1_2_11_144_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7605428"},{"key":"e_1_2_11_145_2","doi-asserted-by":"publisher","DOI":"10.1016\/0531-5565(92)90069-C"},{"key":"e_1_2_11_146_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6408(1996)18:2<173::AID-DVG10>3.0.CO;2-3"},{"key":"e_1_2_11_147_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2007.08.006"},{"key":"e_1_2_11_148_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2275"},{"key":"e_1_2_11_149_2","doi-asserted-by":"publisher","DOI":"10.1124\/mol.105.011494"},{"key":"e_1_2_11_150_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(03)00101-X"},{"key":"e_1_2_11_151_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M201266200"},{"key":"e_1_2_11_152_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.24.6958"},{"key":"e_1_2_11_153_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-2306"},{"key":"e_1_2_11_154_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.09.038"},{"key":"e_1_2_11_155_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1158\/0008-5472.CAN-05-1215","article-title":"In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor","volume":"65","author":"Dikmen ZG","year":"2005","journal-title":"Cancer Res"},{"key":"e_1_2_11_156_2","first-page":"3931","article-title":"A novel telomerase template antagonist (GRN163) as a potential anticancer agent","volume":"63","author":"Asai A","year":"2003","journal-title":"Cancer Res"},{"key":"e_1_2_11_157_2","first-page":"6187","article-title":"Effects of oligonucleotide N3'\u2192P5' thio\u2010phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells","volume":"63","author":"Akiyama M","year":"2003","journal-title":"Cancer Res"},{"key":"e_1_2_11_158_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006477730934"},{"key":"e_1_2_11_159_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32461"},{"key":"e_1_2_11_160_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm711"},{"key":"e_1_2_11_161_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-0793-03"},{"key":"e_1_2_11_162_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206833"},{"key":"e_1_2_11_163_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja017308q"},{"key":"e_1_2_11_164_2","doi-asserted-by":"publisher","DOI":"10.1124\/mol.61.5.1154"},{"key":"e_1_2_11_165_2","first-page":"490","article-title":"GV\u20101001, an injectable telomerase peptide vaccine for the treatment of solid cancers","volume":"9","author":"Nava\u2010Parada P","year":"2007","journal-title":"Curr Opin Mol Ther"},{"key":"e_1_2_11_166_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-006-0145-7"},{"key":"e_1_2_11_167_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603437"},{"key":"e_1_2_11_168_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-12-4322"},{"key":"e_1_2_11_169_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-02-0546"},{"key":"e_1_2_11_170_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.81"}],"container-title":["Hematological Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhon.937","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hon.937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T13:01:43Z","timestamp":1700485303000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hon.937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":169,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["10.1002\/hon.937"],"URL":"https:\/\/doi.org\/10.1002\/hon.937","archive":["Portico"],"relation":{},"ISSN":["0278-0232","1099-1069"],"issn-type":[{"value":"0278-0232","type":"print"},{"value":"1099-1069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}