{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:22:09Z","timestamp":1790392929579,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,3,7]],"date-time":"2011-03-07T00:00:00Z","timestamp":1299456000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hematological Oncology"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recent studies have identified receptor tyrosine kinase\u2010like orphan receptor 1 (ROR1) on the surface of chronic lymphoid leukaemia (CLL) cells. In order to determine whether ROR1 expression is a suitable surrogate marker for the diagnosis of CLL we analysed the mRNA level of ROR1 in different types of non\u2010Hodgkin lymphomas (NHL), and detected elevated levels of ROR1 compared to control peripheral mononuclear cells in several entities (CLL\u2009\u2265\u2009mantle cell lymphoma (MCL)\u2009&gt;\u2009marginal zone lymphoma (MZL)\u2009&gt;&gt;\u2009diffuse large B\u2010cell lymphoma\u2009&gt;\u2009follicular lymphoma). ROR1 protein was expressed intensely on the cell surface of lymphoma cells with leukaemic blood count detected by three colour immunofluorescence. Our results indicate that ROR1 expression is not limited to CLL cases, but it is more prevalent in NHLs, mainly in MCL where it is expressed intensely and MZL where it is expressed moderately, suggesting a general role of ROR1 in lymphoma genesis and\/or maintenance. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hon.948","type":"journal-article","created":{"date-parts":[[2010,7,6]],"date-time":"2010-07-06T17:20:27Z","timestamp":1278436827000},"page":"17-21","source":"Crossref","is-referenced-by-count":72,"title":["ROR1 expression is not a unique marker of CLL"],"prefix":"10.1002","volume":"29","author":[{"given":"G\u00e1bor","family":"Barna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Mihalik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Botond","family":"Tim\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"T\u00f6mb\u00f6l","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Csende","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sebesty\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"B\u00f6d\u00f6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bal\u00e1zs","family":"Csernus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilla","family":"Reiniger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Pet\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e1s","family":"Matolcsy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,7]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2008.08.006"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(95)90146-9"},{"issue":"36","key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"26181","DOI":"10.1016\/S0021-9258(18)35733-8","article-title":"A novel family of cell surface receptors with tyrosine kinase\u2010like domain","volume":"267","author":"Masiakowski P","year":"1992","journal-title":"J Biol Chem"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0712148105"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1258"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.11.1625"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.11.1639"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1823"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23587"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000121405"},{"key":"e_1_2_5_12_2","volume-title":"SHaVJW. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissue","author":"Jaffe ES","year":"2001"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.13239"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.2174\/156652407779940486"},{"issue":"6","key":"e_1_2_5_15_2","first-page":"583","article-title":"The role of oncogenic kinases in human cancer (Review)","volume":"5","author":"Tsatsanis C","year":"2000","journal-title":"Int J Mol Med"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05610"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1082596"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1571"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.222"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-101394"},{"issue":"2","key":"e_1_2_5_21_2","first-page":"273","article-title":"STAT3\u2010induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review)","volume":"19","author":"Katoh M","year":"2007","journal-title":"Int J Mol Med"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-007-0266-2"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-02-139212"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308648100"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-7-13"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature01611"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6690721"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0307194"}],"container-title":["Hematological Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhon.948","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hon.948","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T19:39:14Z","timestamp":1700595554000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hon.948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1002\/hon.948"],"URL":"https:\/\/doi.org\/10.1002\/hon.948","archive":["Portico"],"relation":{},"ISSN":["0278-0232","1099-1069"],"issn-type":[{"value":"0278-0232","type":"print"},{"value":"1099-1069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}