{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T15:40:47Z","timestamp":1786722047601,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002129","name":"Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Prom J of Aust"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Issue Addressed<\/jats:title><jats:p>Obesity in children is one of the most significant public health issues globally. Given the high prevalence of overweight and obesity in children, there is a need to identify effective obesity prevention efforts that can be delivered at scale to improve child health. We aimed to (i) identify obesity prevention interventions targeted at children aged 0\u20132 that have been scaled\u2010up, and their relative efficacy compared to their pre\u2010scale trial, (ii) describe adaptations made, and the extent to which factors related to scalability have been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a rapid review of pre\u2010scale randomised controlled trials targeting nutrition, physical activity and obesity prevention in infants, and calculated the relative effect size for relevant outcomes in the corresponding scaled up trial. We documented adaptations made to the pre\u2010scale trial for scale up, and explored how different components of scalability had been reported according to the Intervention Scalability Assessment Tool.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 14 identified pre\u2010scale trials, only one formal evaluation of the scale\u2010up trial was identified. For body mass index, &lt;10% of the effect was retained, however for nutrition and behavioural outcomes, the proportion of effect retained varied from \u221211.1% to 144%. Significant adaptations to modality were made in the scaled up trial primarily to reduce cost and increase reach of the intervention. Reporting of scalability components varied across the 14 trials, with only one trial reporting information for all assessed components.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The majority of effective interventions targeting obesity prevention in infants have not been evaluated in a scaled up form. The magnitude of effect retained for the single trial that was scaled up was variable. In general, reporting of components of scalability was sub\u2010optimal.<\/jats:p><\/jats:sec><jats:sec><jats:title>So What?<\/jats:title><jats:p>The findings suggest that there is substantial need for the development and rigorous evaluation of obesity prevention interventions in children aged 0\u20132 which are amenable for scale.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hpja.760","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T13:08:42Z","timestamp":1687525722000},"page":"365-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A rapid review of the scalability of interventions targeting obesity prevention in infants"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0836-017X","authenticated-orcid":false,"given":"Sze Lin","family":"Yoong","sequence":"first","affiliation":[{"name":"Global Obesity Centre, Institute for Health Transformation, School of Health and Social Development, Faculty of Health Deakin University  Geelong Australia"},{"name":"School of Medicine and Public Health, College of Health, Medicine and Wellbeing University of Newcastle  Callaghan Australia"},{"name":"Hunter Medical Research Institute  New Lambton Heights Australia"},{"name":"Hunter New England Population Health Unit Hunter New England Local Health District  Wallsend Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6386-3394","authenticated-orcid":false,"given":"Heidi","family":"Turon","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, College of Health, Medicine and Wellbeing University of Newcastle  Callaghan Australia"},{"name":"Hunter Medical Research Institute  New Lambton Heights Australia"},{"name":"Hunter New England Population Health Unit Hunter New England Local Health District  Wallsend Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5759-735X","authenticated-orcid":false,"given":"Carrie K.","family":"Wong","sequence":"additional","affiliation":[{"name":"School of Health Sciences Swinburne University of Technology  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3379-5340","authenticated-orcid":false,"given":"Alice","family":"Grady","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, College of Health, Medicine and Wellbeing University of Newcastle  Callaghan Australia"},{"name":"Hunter Medical Research Institute  New Lambton Heights Australia"},{"name":"Hunter New England Population Health Unit Hunter New England Local Health District  Wallsend Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2677-2327","authenticated-orcid":false,"given":"Nicole","family":"Pearson","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, College of Health, Medicine and Wellbeing University of Newcastle  Callaghan Australia"},{"name":"Hunter Medical Research Institute  New Lambton Heights Australia"},{"name":"Hunter New England Population Health Unit Hunter New England Local Health District  Wallsend Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0470-7663","authenticated-orcid":false,"given":"Rachel","family":"Sutherland","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, College of Health, Medicine and Wellbeing University of Newcastle  Callaghan Australia"},{"name":"Hunter Medical Research Institute  New Lambton Heights Australia"},{"name":"Hunter New England Population Health Unit Hunter New England Local Health District  Wallsend Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,21]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"WHO.Obesity and overweight 2021. 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