{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:44:46Z","timestamp":1786977886209,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Poor medication management may negatively impact the health and functional capacity of older adults. This cross\u2010sectional study aimed to identify medication\u2010related risk factors in home\u2010dwelling residents using a validated self\u2010assessment as part of comprehensive health screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The data were derived from comprehensive health screening (PORI75) for older adults of 75 years living in Western Finland in 2020 and 2021. One of 30 validated measures in health screening focused on identifying medication\u2010related risk factors (LOTTA Checklist). The Checklist items were divided into (1) systemic risk factors (10 items) and (2) potentially drug\u2010induced symptoms (10 items). Polypharmacy was categorized according to the number of used drugs: (1) no polypharmacy (&lt;5 drugs), (2) polypharmacy (\u22655 and &lt;10), and (3) excessive polypharmacy (\u226510). The linearity across these three polypharmacy groups was evaluated using the Cochran\u2013Armitage test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Altogether, 1024 out of 1094 residents who participated in the health screening consented to this study (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009569 in 2020 and\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009459 in 2021). The mean number of all drugs in use was 7.0 (range 0\u221226; SD 4.1), with 71% of the residents using &gt;5 drugs, that is, having polypharmacy. Of the systemic risk factors most common was that the resident had more than one physician responsible for the treatment (48% of the residents), followed by missing drug list (43%), missing regular monitoring (35%), and unclear durations of the medication (35%). The most experienced potentially drug\u2010induced symptoms were self\u2010reported constipation (21%), urinating problems (20%), and unusual tiredness (17%). An increasing number of drugs in use, particularly excessive polypharmacy, was associated with various medication\u2010related risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As a part of comprehensive health screening the LOTTA Checklist provides useful information to prevent medication\u2010related risk factors in home\u2010dwelling older adults. The Checklist could be used to guide planning and implementing health services in the future.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.1196","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T23:10:19Z","timestamp":1681427419000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Self\u2010assessed medication risk factors as part of comprehensive health screening in home\u2010dwelling older adults"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7978-5677","authenticated-orcid":false,"given":"Jonna\u2010Carita","family":"Kanninen","sequence":"first","affiliation":[{"name":"Faculty of Technology Satakunta University of Applied Sciences  Pori Finland"},{"name":"Clinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha","family":"Puustinen","sequence":"additional","affiliation":[{"name":"Clinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy University of Helsinki  Helsinki Finland"},{"name":"Service Unit of Neurology, Satasairaala Central Hospital Satakunta Wellbeing County  Pori Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marja","family":"Airaksinen","sequence":"additional","affiliation":[{"name":"Clinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Kautiainen","sequence":"additional","affiliation":[{"name":"Department of General Practice, Unit of Primary Health Care, Helsinki University Central Hospital University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u2010Liisa","family":"Koivisto","sequence":"additional","affiliation":[{"name":"Public Health and Social Services  Pori Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauliina","family":"Hietasalo","sequence":"additional","affiliation":[{"name":"Public Health and Social Services  Pori Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u2010Maija","family":"Heikkil\u00e4","sequence":"additional","affiliation":[{"name":"Health Center of the City of Pori  Pori Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Kunvik","sequence":"additional","affiliation":[{"name":"Social Security Center of Pori, Faculty of Health and Welfare Satakunta University of Applied Sciences  Pori Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terhi","family":"Toivo","sequence":"additional","affiliation":[{"name":"Tampere University Hospital, Hospital Pharmacy Wellbeing Services County of Pirkanmaa Tampere  Tampere Finland"},{"name":"Clinical Pharmacy Group University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarit","family":"Dimitrow","sequence":"additional","affiliation":[{"name":"Clinical Pharmacy Group, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussi","family":"Bergman","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Turku  Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Holm","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Turku  Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2017.03.002"},{"key":"e_1_2_11_3_1","unstructured":"Ministry of Social Affairs and Health and Association of Finnish Local and Regional Authorities.Quality recommendation to guarantee a good quality of life and improved services for older persons 2020\u20132023. 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