{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T01:48:12Z","timestamp":1776131292462,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Adequate postoperative analgesia and prevention of post\u2010op nausea and vomiting (PONV) are core components of modern day anaesthesia and peri\u2010operative care. As well as contributing to overall morbidity, postoperative pain and PONV are frequently cited as one of the most unpleasant and distressing aspects of surgery for patients. Variation in healthcare delivery is known to exist but has often been poorly described. A first step to understanding the consequences of variation is to describe the extent of variation. We aimed to assess variation in pharmacological strategies to prevent postoperative pain, nausea and vomiting in patients undergoing elective major abdominal surgery at a tertiary hospital in Perth, Western Australia, over a three\u2010month period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We observed considerable variation in prescribing of postoperative analgesia and PONV prophylaxis and suggest that despite adequate evidence based guidelines, they are often overlooked in practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Measurement of the consequences of variation requires randomised clinical trials that evaluate differences in outcome and cost, associated with the strategies that exist within the spectrum of variation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.1335","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T10:51:05Z","timestamp":1686739865000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Variation in prescribing for the prevention of postoperative nausea, vomiting, and pain following abdominal surgery: A retrospective study"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2423-4584","authenticated-orcid":false,"given":"Sarah M.","family":"Kelly","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology National Maternity Hospital Dublin Ireland"},{"name":"St John of God Subiaco Hospital Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miranda","family":"Quenby","sequence":"additional","affiliation":[{"name":"St John of God Subiaco Hospital Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1s B","family":"Corcoran","sequence":"additional","affiliation":[{"name":"St John of God Subiaco Hospital Perth Western Australia Australia"},{"name":"Anaesthesia, Teaching and Research, Faculty of Nursing, Medicine and Health Sciences, Central Clinical School Monash University  Victoria Melbourne Australia"},{"name":"Royal Perth Hospital Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Webb","sequence":"additional","affiliation":[{"name":"St John of God Subiaco Hospital Perth Western Australia Australia"},{"name":"School of Epidemiology and Preventive Medicine Monash University Victoria Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4860-9232","authenticated-orcid":false,"given":"Paul A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"St John of God Subiaco Hospital Perth Western Australia Australia"},{"name":"Division of Obstetrics and Gynaecology, Medical School University of Western Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.693"},{"issue":"3","key":"e_1_2_10_3_1","first-page":"388","article-title":"Postoperative nausea and vomiting: a simple yet complex problem","volume":"10","author":"Nagarekha D","year":"2016","journal-title":"Anesthesia"},{"key":"e_1_2_10_4_1","volume-title":"Australian Commission on Safety and Quality in Health Care","author":"Healthcare Variation","year":"2021"},{"key":"e_1_2_10_5_1","first-page":"58","volume-title":"Acute Pain Management","author":"Schug S","year":"2020"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31823c1030"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004833"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2019.0091"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2018.08.035"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-8180(01)00283-5"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen230"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000295230.55439.f4"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2019.83293"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32834a3d81"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.1335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T22:21:21Z","timestamp":1692483681000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.1335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/hsr2.1335"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.1335","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2023-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e1335"}}