{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T23:49:50Z","timestamp":1787356190230,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Skin grafting is the single most effective method to close a chronic wound. The current standard of care is to use meshed split thickness skin grafts. This entails the use of surgical instruments that need to be autoclaved and to have a power source, which usually requires an OR facility. The minced skin technique uses single use, presterilized instruments and the procedure can be done under local anesthesia, by a wound care practitioner, in a wound clinic, a physician's office or even at the bedside. The current study was designed to determine if the results from micrografting were non inferior to conventional mesh grafting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a prospective non inferiority study, 26 chronic ulcers were treated with micrografting (MSG) and 24 with conventional mesh grafts 1:3 (control group\u2010CG) in a total of 21 patients, 10 male and 11 female. The donor site areas in the MSG group were predetermined to 2.5\u2009\u00d7\u20095\u2009cm and the mesh grafts expansion was set at 1:3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In the first weeks postoperatively, micrograft healing initially lagged behind the conventional mesh grafts but at 60 days after grafting, all MSG wounds were healed. The MSG wounds had better pigmentation, less itching,\u00a0and less scarring. The micrografting procedure was easy to learn and expeditious to perform. The MSG mean expansion was 9.1 compared to three times (CG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The MSG procedure is not inferior to conventional mesh grafting, requires smaller donor sites, and can be done with single use instruments, under local anesthesia, with early discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.1353","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T01:35:17Z","timestamp":1687570517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Minced skin grafts for chronic wounds compared to conventional mesh grafts"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9496-3024","authenticated-orcid":false,"given":"D\u00e9bora C.","family":"Sanches\u2010Pinto","sequence":"first","affiliation":[{"name":"Divis\u00e3o de Cirurgia Pl\u00e1stica e Queimaduras. Clinicas Hospital \u2010 School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elof","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Gomez","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Cirurgia Pl\u00e1stica e Queimaduras. Clinicas Hospital \u2010 School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria P. T.","family":"Nunes","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Gemperli","sequence":"additional","affiliation":[{"name":"Divis\u00e3o de Cirurgia Pl\u00e1stica e Queimaduras. Clinicas Hospital \u2010 School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco G.","family":"Soriano","sequence":"additional","affiliation":[{"name":"School of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12994"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2015.0635"},{"key":"e_1_2_10_4_1","first-page":"289","article-title":"Wounds and ulcers: back to the old nomenclature","volume":"22","author":"Hermans MH","year":"2010","journal-title":"Wounds"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12387"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009283"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.113.300268"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2015.01.031"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2020.04.583"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2021.02.007"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000733724.87630.d6"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2021.26.Sup9.S6"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2022.31.Sup8a.S5"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-16-9816-3_5"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(58)90975-9"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196409000-00011"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2017.01.015"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.2001.6331"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318241289c"},{"key":"e_1_2_10_20_1","first-page":"14","article-title":"Fast and standardized skin grafting of leg wounds with a new technique: report of 2 cases and review of previous methods","volume":"16","author":"Hamnerius N","year":"2016","journal-title":"Eplasty"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0b013e3181e4c8aa"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000001871"},{"issue":"1","key":"e_1_2_10_23_1","first-page":"S17","article-title":"Minced skin grafts can be expanded up to 500 times to re\u2013epitheliaze full\u2013thickness burns","volume":"43","author":"Nuutila K","year":"2022","journal-title":"J Burn Care Res"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/193293a0"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2020.1232"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-199005000-00014"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM190912231612601"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181ccdc42"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2018.11.003"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.1353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T18:19:45Z","timestamp":1692469185000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.1353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/hsr2.1353"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.1353","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2023-02-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e1353"}}