{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:28:18Z","timestamp":1792621698042,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Key messages<\/jats:title>\n                  <jats:p>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>The most appropriate management of recurrent Hidradenitis Suppurativa (HS) lesions consists of wide surgical removal of the lesions with subsequent healing by second intention. Successful wound healing depends on the choice of an adequate wound dressing, targeted to the features of the wound.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>We enrolled 25 patients randomized into three groups according to the advanced dressing used in second intention healing of postsurgical wounds (standard therapy, an oxygen\u2010enriched oil\u2010based medical device with prolonged release of reactive oxygen species [ROS], ultra\u2010portable negative pressure therapy). Data on wound size, clinical appearance of the wound bed, and pain experienced by the patient were collected twice a week for 4 weeks<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>No statistically significant differences were observed between the different groups evaluated. Oxygen\u2010enriched oil\u2010based medical device with prolonged release of ROS can be included in the principle of HS\u2014tissue, inflammation, moisture, and epithelium (TIME).<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1002\/hsr2.1582","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T22:38:39Z","timestamp":1697063919000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Advanced wound management approaches in Hidradenitis Suppurativa postsurgical lesions"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0795-0338","authenticated-orcid":false,"given":"Alessandra","family":"Michelucci","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Pisa Pisa 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University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Dini","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.08.090"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12823"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14770"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13282"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.11.s2.1.x"},{"issue":"9","key":"e_1_2_10_7_1","first-page":"222","article-title":"HS\u2010TIME: a modified TIME concept in hidradenitis suppurativa topical management","volume":"31","author":"Oranges 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