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The aim of the prison HCV\u2010intensive test and treat initiative was to screen over 95% of all prison residents for HCV infection within a defined number of days determined by the size of the prison population and to initiate treatment within 7\u221214 days of a positive HCV RNA diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An HCV\u2010intensive test and treat toolkit was developed based on learnings from pilot HCV\u2010intensive test and treat events. From January 2020 to September 2021, 13 HCV\u2010intensive test and treat events took place at prisons in England selected based on high levels of reception blood\u2010borne virus testing and good access to peers from The Hepatitis C Trust.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among a total of 8487 residents, 8139 (95.9%) underwent testing for HCV. Across the 13 prisons included, HCV antibody and RNA prevalence was 8.2% and 1.5%, respectively. The treatment initiation rate among HCV RNA\u2010positive individuals (<jats:italic>n<\/jats:italic>\u2009=\u2009124) was 79.0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The HCV\u2010intensive test and treat initiative presented here provides a feasible and rapid test\u2010and\u2010treat process to achieve HCV elimination within individual prisons. The HCV\u2010intensive test and treat toolkit can be adapted for rapid HCV testing and treatment events at other prisons in the United Kingdom and worldwide.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.1724","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T05:35:19Z","timestamp":1703050519000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Chronic hepatitis C elimination prison initiative: HCV\u2010intensive test and treat, a whole prisoner population HCV test\u2010and\u2010treat program in England"],"prefix":"10.1002","volume":"6","author":[{"given":"Rachel","family":"Halford","sequence":"first","affiliation":[{"name":"The Hepatitis C Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Christensen","sequence":"additional","affiliation":[{"name":"The Hepatitis C Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Cox","sequence":"additional","affiliation":[{"name":"The Hepatitis C Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Sheehan","sequence":"additional","affiliation":[{"name":"The Hepatitis C Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Brew","sequence":"additional","affiliation":[{"name":"Practice Plus Group Berkshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Gillyon\u2010Powell","sequence":"additional","affiliation":[{"name":"NHS England and NHS Improvement Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Threadgold","sequence":"additional","affiliation":[{"name":"NHS England and NHS Improvement Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9amonn","family":"O'Moore","sequence":"additional","affiliation":[{"name":"UK Health and Security Agency London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J. 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