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Intracardiac echocardiography (ICE), a new imaging modality, is a promising strategy for guiding LAAC. This review highlights the various strategies for ICE\u2010guided\u2010LAAC as an option for clinical policy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive literature search was conducted of PubMed, ScienceDirect, Ovid Web of Science, SpringerLink, and other notable databases to identify recent peer\u2010reviewed clinical trials, reviews, and research articles related to ICE and its application in the guidance of LAAC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Various methods are used to evaluate the spatial structure and dimensions of the LAA. The main techniques for guiding LAAC are transesophageal echocardiography (TEE), cardiac computed tomography (CTA), and ICE. Among these techniques, the advantages of ICE typically include (1) multiangle and real\u2010time assessment of intracardiac structure, (2) a reduction in procedural fluoroscopy, (3) reduced operation time and improved workflow in the catheterization laboratory, and (4) the avoidance of general anesthesia and the early detection of complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ICE is a promising strategy for the guidance of LAAC. Among the most advanced and recent technological innovations in cardiovascular imaging in general and volume imaging in particular, ICE offers greater efficacy and safety.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.1762","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T08:52:03Z","timestamp":1702975923000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intracardiac echocardiography is a promising strategy for guiding closure of the left atrial appendage"],"prefix":"10.1002","volume":"6","author":[{"given":"Xueyan","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Cardiology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou Zhejiang P.R. 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