{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:54:09Z","timestamp":1753869249437,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172204","82372517"],"award-info":[{"award-number":["82172204","82372517"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>To assess patient comfort, wound healing, and scarring at the 6\u2010month follow\u2010up of split\u2010skin graft donor sites treated with Ba\u2010Hao burn ointment (BHBO) gauze, a compound preparation of traditional Chinese medicine since 1970s, compared with petrolatum gauze.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty patients admitted to the Department of Burns of the First Affiliated Hospital of Anhui Medical University between September 2021 and September 2022 participated in this randomized, prospective, self\u2010control clinical study. After harvesting the split skin, donor sites were divided into two parts along the midline. BHBO gauze was applied to half of the donor wounds, and petrolatum gauze was applied to the other half. The wound healing time, pain scores on the postoperative Days 3, 6, and 9, and Vancouver Scar Scale (VSS) score at the 6\u2010month follow\u2010up were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The wound healing time was significantly shorter in the BHBO group than in the control group (10.07\u2009\u00b1\u20091.48 days vs. 11.50\u2009\u00b1\u20091.74 days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). On postoperative Days 3 and 6, the pain scores quantified by visual analog scores were significantly lower in the BHBO group than in the control group (5.33\u2009\u00b1\u20091.54 and 4.17\u2009\u00b1\u20091.51, respectively vs. 7.57\u2009\u00b1\u20091.41 and 5.20\u2009\u00b1\u20091.47, respectively). The difference in the visual analog scale score on postoperative Day 9 between the groups was not significant (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Microbiological assessment revealed the absence of bacterial contamination in both groups. At the 6\u2010month follow up, the VSS score was significantly lower in the BHBO group (6.67\u2009\u00b1\u20091.92) than in the control group (9.57\u2009\u00b1\u20091.55).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>BHBO resulted in faster donor\u2010site healing, reduced postoperative pain, and improved scar quality at the 6\u2010month follow\u2010up than petrolatum gauze alone.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.1988","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T05:19:28Z","timestamp":1712121568000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Ba\u2010Hao burn ointment gauze and petrolatum gauze in split graft donor site healing: A randomized, prospective, and self\u2010control study"],"prefix":"10.1002","volume":"7","author":[{"given":"Wen\u2010Jing","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Graduate School Anhui University of Chinese Medicine Hefei Anhui PR China"},{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"},{"name":"Department of Integrated Traditional Chinese and Western Medicine Anhui Medical University Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han\u2010Ying","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Graduate School Anhui University of Chinese Medicine Hefei Anhui PR China"},{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"},{"name":"Department of Integrated Traditional Chinese and Western Medicine Anhui Medical University Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Graduate School Anhui University of Chinese Medicine Hefei Anhui PR China"},{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"},{"name":"Department of Integrated Traditional Chinese and Western Medicine Anhui Medical University Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0508-3581","authenticated-orcid":false,"given":"Xu\u2010Lin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Burns The First Affiliated Hospital of Anhui Medical University Hefei Anhui PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13518"},{"key":"e_1_2_11_3_1","first-page":"121","article-title":"Effect of wet burn cream on residual wound in the donor skin area","volume":"27","author":"Xin\u2010lei Y","year":"2021","journal-title":"Contemp Med"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2020.03.006"},{"key":"e_1_2_11_5_1","first-page":"112","article-title":"Research progress of external application of traditional Chinese medicine in the treatment of 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