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As serum miRNAs are potentially appropriate markers, we investigated miR\u201026a and miR\u201026b expression levels in pregnant women with and without gestational diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Demographic and clinical characteristics of 40 gestational diabetic patients and 40 healthy controls were assessed. The expression level of miR\u201026a and miR\u201026b microRNAs was measured by real\u2010time PCR. Statistical analysis was done with GraphPad Prism software (version 8.4.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>The findings of this study showed that the expression level of miR\u201026a and miR\u201026b increased in women with gestational diabetes compared with healthy pregnant women, but the increase in expression was only significant for miR\u201026a (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>According to the statistical and ROC curves, we suggest miR\u201026a as a potential biomarker for the early diagnosis of gestational diabetes mellitus.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.2152","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T03:59:21Z","timestamp":1717387161000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Are miR\u201026a and miR\u201026b microRNAs potent prognostic markers of gestational diabetes?"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4536-6041","authenticated-orcid":false,"given":"Hori","family":"Ghaneialvar","sequence":"first","affiliation":[{"name":"Biotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Ilam Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3456-5603","authenticated-orcid":false,"given":"Mahdieh Mehrab","family":"Mohseni","sequence":"additional","affiliation":[{"name":"Student Research Committee Ilam University of Medical Sciences Ilam Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9928-8627","authenticated-orcid":false,"given":"Azra","family":"Kenarkoohi","sequence":"additional","affiliation":[{"name":"Department of Laboratory Sciences, School of Allied Medical Sciences Ilam University of Medical Sciences Ilam Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6242-5803","authenticated-orcid":false,"given":"Saeed","family":"Kakaee","sequence":"additional","affiliation":[{"name":"Biotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Ilam Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/761617"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109119"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113217"},{"key":"e_1_2_12_5_1","first-page":"85","article-title":"Mechanisms of actions of some bioactive anti\u2010diabetic principles from phytochemicals of medicinal plants: a review","volume":"9","author":"Aba PE","year":"2018","journal-title":"Indian J Nat Prod Resour"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60731-5"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19113342"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.133855"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2022.113897"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-016-0607-5"},{"issue":"1","key":"e_1_2_12_11_1","first-page":"S17","article-title":"2. 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