{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:21:22Z","timestamp":1755217282019,"version":"3.43.0"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of prophylactic drainage after laparoscopic cholecystectomy has been a routine practice for many years. However, the debate surrounding using it stems from conflicting evidence regarding its potential benefits and risks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent laparoscopic cholecystectomy from February 1, 2022, to November 30, 2022, at Aleppo University Hospital were enrolled according to our previously registered protocol (NCT05267860).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 232 patients (117 in the drainage group [DG], and 115 in the non\u2010drainage group [NDG]). There was no statistical difference in the patients'\u00a0main characteristics, comorbidities, and laboratory findings. The duration of the surgical operation in NDG (mean\u2009=\u200944.92, SD\u2009=\u20091.85) was shorter than in DG (mean 55.14, SD\u2009=\u20092.14), with (<jats:italic>p<\/jats:italic>\u2009=\u20090.039) statistically significant, which indicates that the use of the drainage led to a prolongation of the surgical operation. The total number of complicated cases reached 22 (9.48%) cases (DG\u2009=\u20099 vs.\u00a0NDG\u2009=\u200913, <jats:italic>p<\/jats:italic>\u2009=\u20090.348) as follows: bleeding (<jats:italic>n<\/jats:italic>\u2009=\u20091) (DG\u2009=\u20091 vs.\u00a0NDG\u2009=\u20090; <jats:italic>p<\/jats:italic>\u2009=\u20090.320), bile leak with no established bile duct injury (<jats:italic>n<\/jats:italic>\u2009=\u20091) (DG\u2009=\u20091 vs.\u00a0NDG\u2009=\u20090; <jats:italic>p<\/jats:italic>\u2009=\u20090.320), wound infection (<jats:italic>n<\/jats:italic>\u2009=\u200912) (DG\u2009=\u20094 vs.\u00a0NDG\u2009=\u20098; <jats:italic>p<\/jats:italic>\u2009=\u20090.443), urinary tract infection (<jats:italic>n<\/jats:italic>\u2009=\u20093) (DG\u2009=\u20090 vs.\u00a0NDG\u2009=\u20093; <jats:italic>p<\/jats:italic>\u2009=\u20090.079), prolonged shoulder pain (<jats:italic>n<\/jats:italic>\u2009=\u20092) (DG\u2009=\u20090 vs.\u00a0NDG\u2009=\u20092; <jats:italic>p<\/jats:italic>\u2009=\u20090.152), and acute pancreatitis (<jats:italic>n<\/jats:italic>\u2009=\u20091) (DG\u2009=\u20091 vs.\u00a0NDG\u2009=\u20090; <jats:italic>p<\/jats:italic>\u2009=\u20090.144).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Based on the results of our study, the use of prophylactic drainage was safe, but ineffective, as it did not improve the outcomes statistically significantly or worsen them, which is consistent with previous studies highlighting the need for personalized patient care in this setting.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.2284","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T01:13:50Z","timestamp":1723166030000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The efficacy and safety of using prophylactic abdominal drainage after laparoscopic cholecystectomy: A randomized control 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Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8639-5263","authenticated-orcid":false,"given":"Yaman","family":"Nerabani","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abd Alazeez","family":"Atli","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Arnaout","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Arnaout","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel","family":"Bsata","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Kayali","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nehad","family":"Mahli","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Al\u2010Haj","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aleppo University Hospital University of Aleppo  Aleppo Syrian Arab 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