{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:09Z","timestamp":1786977909036,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T00:00:00Z","timestamp":1631577600000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>Our study aimed to establish safer methods to manage home blood transfusion by using a remote vital signs data monitoring system. Home care is administered for patients with various medical disorders; however, home blood transfusion remains challenging owing to the risk of transfusion\u2010related complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We set up a remote vital signs data monitoring system to improve the safety of home blood transfusions. Using an Internet\u2010based vital signs data monitoring system, the heart rate, electrocardiography, respiration rate, and percutaneous oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ) were monitored and recorded during the entire home transfusion period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten transfusions in three patients were monitored; two of the patients had an abnormality in a single vital sign (decreased SpO\n                      <jats:sub>2<\/jats:sub>\n                      decrease and increased respiratory rate); these were not transfusion\u2010related complications. Vital sign anomalies also occur because of errors in using the measurement device and noise associated with body movements. The presence of abnormalities in at least two vital signs among SpO\n                      <jats:sub>2<\/jats:sub>\n                      decrease, tachycardia, and increased respiratory rate that persisted for &gt;5\u2009minutes was defined as a complicated vital sign abnormality (CVSA). There were no severe transfusion\u2010related complications with CVSA in the present study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study indicates the feasibility and sustainability of real\u2010time remote monitoring of vital signs for the safety of home transfusion. Although CVSA may function as an indicator of severe transfusion\u2010related complications, these findings need to be confirmed with further studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.380","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T13:11:02Z","timestamp":1631625062000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Remote vital signs data monitoring during home blood transfusion: A pilot study"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9286-6909","authenticated-orcid":false,"given":"Akinori","family":"Nishikawa","sequence":"first","affiliation":[{"name":"Division of Blood Transfusion Wakayama Medical University Hospital  Wakayama Japan"},{"name":"Department of Hematology\/Oncology Wakayama Medical University Hospital  Wakayama Japan"},{"name":"Division of Medical Information Wakayama Medical University Hospital  Wakayama Japan"},{"name":"Akasaka Clinic  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Fujimori","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Internal Medicine Department of Transfusion Medicine and Cellular Therapy Hyogo College of Medicine  Nishinomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Sakano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Okayama University Graduate School of Medicine  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiki","family":"Mushino","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology Wakayama Medical University Hospital  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinobu","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology Wakayama Medical University Hospital  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Okayama University Graduate School of Medicine  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Akasaka","sequence":"additional","affiliation":[{"name":"Akasaka Clinic  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Sonoki","sequence":"additional","affiliation":[{"name":"Division of Blood Transfusion Wakayama Medical University Hospital  Wakayama Japan"},{"name":"Department of Hematology\/Oncology Wakayama Medical University Hospital  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/hsc.12831"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2005.00574.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2016.01.012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14816"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.63.664"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1586\/17434440.2015.1050957"},{"key":"e_1_2_11_8_1","first-page":"299","article-title":"Early detection of a blood transfusion reaction utilizing a wireless remote monitoring device","volume":"21","author":"Card E","year":"2012","journal-title":"Medsurg Nurs"},{"key":"e_1_2_11_9_1","first-page":"52","article-title":"The trial of telemedicine in home medical care using a remote real\u2010time monitoring system; experience of five cases","volume":"10","author":"Sakano N","year":"2014","journal-title":"Jpn J Telemed Telecare"},{"key":"e_1_2_11_10_1","first-page":"4","article-title":"The ISBT working party on haemovigilance","volume":"68","author":"Robillard P","year":"2006","journal-title":"Transfus Today"},{"key":"e_1_2_11_11_1","unstructured":"Survey on adverse events in blood transfusion in Japan 2016. Japanese Society for Transfusion and Cell Therapy Hemovigilance subcommittee http:\/\/yuketsu.jstmct.or.jp\/wp-content\/uploads\/2018\/09\/ab4f43512e5f26ccac41b282937. Accessed August 5 2019."},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2012.01.010"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.64.733"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.64.529"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.380","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.380","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.380","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T04:19:32Z","timestamp":1693282772000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1002\/hsr2.380"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.380","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"2021-01-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e380"}}