{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:33:55Z","timestamp":1778686435059,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Acute respiratory distress syndrome <jats:bold>(<\/jats:bold>ARDS) demonstrates several image patterns on high\u2010resolution computed tomography (HRCT). The purpose of this study was to investigate the relationship between specific HRCT findings and the prognosis of ARDS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cohort study performed in a single hospital in Japan. We categorized HRCT findings into three distribution patterns: diffuse, subpleural sparing, and dorsal patterns. All patterns were assessed at three levels of each lung. Multivariable logistic regression analysis was used to identify parameters associated with in\u2010hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 144 patients with ARDS (age: 72\u2009\u00b1\u200916\u2009years, 112 men) were included in the study. The in\u2010hospital mortality rate was 42% (survivors, n\u00a0=\u00a083; nonsurvivors, n\u00a0=\u00a061). Nonsurvivors were significantly older (70\u2009\u00b1\u200917 vs 76\u2009\u00b1\u200913, <jats:italic>P<\/jats:italic>\u00a0=\u20090.01) and had lower serum albumin levels (<jats:italic>P<\/jats:italic>\u00a0=\u20090.01), more traction bronchiectasis (<jats:italic>P<\/jats:italic>\u00a0=\u20090.02), and more diffuse pattern (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001) than survivors. The presence of diffuse patterns was an independent adverse prognostic factor for predicting mortality (odds ratio, 1.32; 95% confidence interval [CI]: 1.08\u20101.61, <jats:italic>P<\/jats:italic>\u00a0=\u20090.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HRCT distribution patterns may predict mortality in ARDS patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.418","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T08:09:45Z","timestamp":1633853385000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["High\u2010resolution computed tomography for the prediction of mortality in acute respiratory distress syndrome: A retrospective cohort study"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3129-916X","authenticated-orcid":false,"given":"Ryosuke","family":"Imai","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Thoracic Center, St. Luke's International Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Thoracic Center, St. Luke's International Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Graduate School of Public Health St. Luke's International University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohide","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Thoracic Center, St. Luke's International Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"issue":"23","key":"e_1_2_11_2_1","first-page":"2526","article-title":"Acute respiratory distress syndrome","volume":"307","author":"Ranieri 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